Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer m
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FLZ alleviates the memory deficits in transgenic mouse model of Alzheimer's disease via decreasing beta-amyloid production and tau hyperphosphorylationIntranasal "painless" human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 miceNeurofibrillary tangles and the deposition of a beta amyloid peptide with a novel N-terminal epitope in the brains of wild Tsushima leopard catsAPP as a Protective Factor in Acute Neuronal Insults.Disruption of amyloid plaques integrity affects the soluble oligomers content from Alzheimer disease brains.Amyloid-β precursor protein promotes cell proliferation and motility of advanced breast cancer.Identification of a role for the PI3K/AKT/mTOR signaling pathway in innate immune cellsMiR-126 Regulates Growth Factor Activities and Vulnerability to Toxic Insult in Neurons.Holo-APP and G-protein-mediated signaling are required for sAPPα-induced activation of the Akt survival pathway.The Molecular Mechanism of Amyloid β42 Peptide Toxicity: The Role of Sphingosine Kinase-1 and Mitochondrial Sirtuinsα-Secretase-derived fragment of cellular prion, N1, protects against monomeric and oligomeric amyloid β (Aβ)-associated cell death.Osmotin attenuates amyloid beta-induced memory impairment, tau phosphorylation and neurodegeneration in the mouse hippocampus.The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer's disease.Presynaptic Aβ40 prevents synapse addition in the adult Drosophila neuromuscular junction.1-42 β-amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death.Mitochondrial dysfunction and cell death in neurodegenerative diseases through nitroxidative stressAPP Receptor? To Be or Not To Be.Epicatechin Plus Treadmill Exercise are Neuroprotective Against Moderate-stage Amyloid Precursor Protein/Presenilin 1 MiceAmyloid β-peptide (1-42)-induced oxidative stress in Alzheimer disease: importance in disease pathogenesis and progression.Amyloid beta-induced glycogen synthase kinase 3β phosphorylated VDAC1 in Alzheimer's disease: implications for synaptic dysfunction and neuronal damageAmyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D-serine homeostasis.Impaired retrograde transport of axonal autophagosomes contributes to autophagic stress in Alzheimer's disease neurons.Roles of amyloid precursor protein family members in neuroprotection, stress signaling and aging.The role of the dysfunctional akt-related pathway in cancer: establishment and maintenance of a malignant cell phenotype, resistance to therapy, and future strategies for drug development.Brain-Derived Neurotrophic Factor in Alzheimer's Disease: Risk, Mechanisms, and Therapy.The Essential Role of Soluble Aβ Oligomers in Alzheimer's Disease.Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells.Restoring Soluble Amyloid Precursor Protein α Functions as a Potential Treatment for Alzheimer's Disease.Structure and Synaptic Function of Metal Binding to the Amyloid Precursor Protein and its Proteolytic Fragments.Altered amyloid precursor protein processing regulates glucose uptake and oxidation in cultured rodent myotubes.Glucocorticoid-Induced Leucine Zipper in Central Nervous System Health and Disease.Expression and Processing of Amyloid Precursor Protein in Vascular Endothelium.Role of APP Interactions with Heterotrimeric G Proteins: Physiological Functions and Pathological ConsequencesThe Effects of Astilbin on Cognitive Impairments in a Transgenic Mouse Model of Alzheimer's Disease.Astroglial connexin43 contributes to neuronal suffering in a mouse model of Alzheimer's diseaseAbnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer's mice hippocampus.Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.Amyloid β inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonistβ-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice.Fucoxanthin, a Marine Carotenoid, Attenuates β-Amyloid Oligomer-Induced Neurotoxicity Possibly via Regulating the PI3K/Akt and the ERK Pathways in SH-SY5Y Cells.
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P2860
Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer m
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Age-dependent accumulation of ...... K-3beta pathway in Alzheimer m
@en
Age-dependent accumulation of soluble amyloid beta
@nl
type
label
Age-dependent accumulation of ...... K-3beta pathway in Alzheimer m
@en
Age-dependent accumulation of soluble amyloid beta
@nl
prefLabel
Age-dependent accumulation of ...... K-3beta pathway in Alzheimer m
@en
Age-dependent accumulation of soluble amyloid beta
@nl
P2093
P2860
P50
P356
P1476
Age-dependent accumulation of ...... K-3beta pathway in Alzheimer m
@en
P2093
Cristina Caballero
Elisabeth Sanchez-Mejias
Irene Carmona-Cuenca
Raquel Sanchez-Varo
P2860
P304
18414-18425
P356
10.1074/JBC.M110.209718
P407
P50
P577
2011-04-01T00:00:00Z