Entamoeba histolytica cysteine proteinases with interleukin-1 beta converting enzyme (ICE) activity cause intestinal inflammation and tissue damage in amoebiasis.
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Immune Response of Amebiasis and Immune Evasion by Entamoeba histolytica.Inflammasome/IL-1β Responses to Streptococcal PathogensToll-like receptor signaling activation by Entamoeba histolytica induces beta defensin 2 in human colonic epithelial cells: its possible role as an element of the innate immune responseOverexpression of Differentially Expressed Genes Identified in Non-pathogenic and Pathogenic Entamoeba histolytica Clones Allow Identification of New Pathogenicity Factors Involved in Amoebic Liver Abscess Formation.Tissue destruction and invasion by Entamoeba histolytica.A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target.Vaccine prospects for amebiasis.An ex-vivo human intestinal model to study Entamoeba histolytica pathogenesis.Resistance of Entamoeba histolytica to the cysteine proteinase inhibitor E64 is associated with secretion of pro-enzymes and reduced pathogenicity.Transcriptional silencing of multiple genes in trophozoites of Entamoeba histolytica.Use of recombinant Entamoeba histolytica cysteine proteinase 1 to identify a potent inhibitor of amebic invasion in a human colonic model.The Entamoeba histolytica genome: primary structure and expression of proteolytic enzymes.The interplay between Entamoeba and enteropathogenic bacteria modulates epithelial cell damage.Proteomic comparison of Entamoeba histolytica and Entamoeba dispar and the role of E. histolytica alcohol dehydrogenase 3 in virulence.IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation.Blockade of caspases inhibits amebic liver abscess formation in a mouse model of disease.A surface amebic cysteine proteinase inactivates interleukin-18.Transcriptional silencing of an amoebapore gene in Entamoeba histolytica: molecular analysis and effect on pathogenicityThe intestinal protozoan parasite Entamoeba histolytica contains 20 cysteine protease genes, of which only a small subset is expressed during in vitro cultivation.Systemic and mucosal responses to oral administration of excretory and secretory antigens from Giardia intestinalisBreaking the species barrier: use of SCID mouse-human chimeras for the study of human infectious diseases.The NLRP3 Inflammasome Is a Pathogen Sensor for Invasive Entamoeba histolytica via Activation of α5β1 Integrin at the Macrophage-Amebae Intercellular Junction.Tumor necrosis factor alpha is a key mediator of gut inflammation seen in amebic colitis in human intestine in the SCID mouse-human intestinal xenograft model of disease.Host-parasite interaction: parasite-derived and -induced proteases that degrade human extracellular matrix.Blastocystis ratti contains cysteine proteases that mediate interleukin-8 response from human intestinal epithelial cells in an NF-kappaB-dependent manner.Proteases from Entamoeba spp. and Pathogenic Free-Living Amoebae as Virulence Factors.Amebic infection in humans.Peroxynitrite and peroxiredoxin in the pathogenesis of experimental amebic liver abscess.MUC2 Mucin and Butyrate Contribute to the Synthesis of the Antimicrobial Peptide Cathelicidin in Response to Entamoeba histolytica- and Dextran Sodium Sulfate-Induced Colitis.Immune responses against protozoan parasites: a focus on the emerging role of Nod-like receptors.Regulation of intestinal permeability: The role of proteasesEntamoeba histolytica cysteine proteinases disrupt the polymeric structure of colonic mucin and alter its protective functionProstaglandin E2 produced by Entamoeba histolytica binds to EP4 receptors and stimulates interleukin-8 production in human colonic cells.Suppression of NF-kappaB activation by Entamoeba histolytica in intestinal epithelial cells is mediated by heat shock protein 27.Expression of amoebapores is required for full expression of Entamoeba histolytica virulence in amebic liver abscess but is not necessary for the induction of inflammation or tissue damage in amebic colitis.BFA-sensitive and insensitive exocytic pathways in Entamoeba histolytica trophozoites: their relationship to pathogenesis.Identification of an Entamoeba histolytica serine-, threonine-, and isoleucine-rich protein with roles in adhesion and cytotoxicity.Colonic luminal proteases activate colonocyte proteinase-activated receptor-2 and regulate paracellular permeability in mice.Amebic cysteine proteinase 2 (EhCP2) plays either a minor or no role in tissue damage in acute experimental amebic liver abscess in hamsters.Proteolysis of enteric cell villin by Entamoeba histolytica cysteine proteinases.
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Entamoeba histolytica cysteine proteinases with interleukin-1 beta converting enzyme (ICE) activity cause intestinal inflammation and tissue damage in amoebiasis.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
@zh-cn
2000年学术文章
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2000年学术文章
@zh-my
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name
Entamoeba histolytica cysteine ...... d tissue damage in amoebiasis.
@en
Entamoeba histolytica cysteine proteinases with interleukin-1 beta converting enzyme
@nl
type
label
Entamoeba histolytica cysteine ...... d tissue damage in amoebiasis.
@en
Entamoeba histolytica cysteine proteinases with interleukin-1 beta converting enzyme
@nl
prefLabel
Entamoeba histolytica cysteine ...... d tissue damage in amoebiasis.
@en
Entamoeba histolytica cysteine proteinases with interleukin-1 beta converting enzyme
@nl
P2093
P2860
P921
P1476
Entamoeba histolytica cysteine ...... d tissue damage in amoebiasis.
@en
P2093
P2860
P304
P356
10.1046/J.1365-2958.2000.02037.X
P407
P577
2000-08-01T00:00:00Z