Fly-casting in protein-DNA binding: frustration between protein folding and electrostatics facilitates target recognition.
about
The Arginine-Rich RNA-Binding Motif of HIV-1 Rev Is Intrinsically Disordered and Folds upon RRE BindingA role for both conformational selection and induced fit in ligand binding by the LAO proteinElectrostatically accelerated encounter and folding for facile recognition of intrinsically disordered proteinsFunctional role of ribosomal signaturesKinetic consequences of native state optimization of surface-exposed electrostatic interactions in the Fyn SH3 domain.Advantages of proteins being disordered.Protective epitopes of the Plasmodium falciparum SERA5 malaria vaccine reside in intrinsically unstructured N-terminal repetitive sequences.Type 1 and Type 2 scenarios in hydrogen exchange mass spectrometry studies on protein-ligand complexes.Electrostatics, structure prediction, and the energy landscapes for protein folding and binding.Direct visualization reveals dynamics of a transient intermediate during protein assembly.On the role of residue phosphorylation in 14-3-3 partners: AANAT as a case study.Molecular dynamics simulation of phosphorylated KID post-translational modification.Predicting Protein-protein Association Rates using Coarse-grained Simulation and Machine Learning.An overview of the importance of conformational flexibility in gene regulation by the transcription factors.Electrostatic forces govern the binding mechanism of intrinsically disordered histone chaperones.Capillarity theory for the fly-casting mechanism.Nonnative interactions in coupled folding and binding processes of intrinsically disordered proteins.Multi-scaled explorations of binding-induced folding of intrinsically disordered protein inhibitor IA3 to its target enzyme.Net charge per residue modulates conformational ensembles of intrinsically disordered proteinsProtein dynamics at Eph receptor-ligand interfaces as revealed by crystallography, NMR and MD simulations.Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation.Importance of electrostatic interactions in the association of intrinsically disordered histone chaperone Chz1 and histone H2A.Z-H2B.DNA search efficiency is modulated by charge composition and distribution in the intrinsically disordered tail.cgDNA: a software package for the prediction of sequence-dependent coarse-grain free energies of B-form DNAComplex energy landscape of a giant repeat protein.Frustration in biomoleculesMutations in DNA-binding loop of NFAT5 transcription factor produce unique outcomes on protein-DNA binding and dynamics.DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex.Intra- and intermolecular translocation of the bi-domain transcription factor Oct1 characterized by liquid crystal and paramagnetic NMR.Dynamic conformational change regulates the protein-DNA recognition: an investigation on binding of a Y-family polymerase to its target DNA.Exploring translocation of proteins on DNA by NMRQuantitative analysis of multisite protein-ligand interactions by NMR: binding of intrinsically disordered p53 transactivation subdomains with the TAZ2 domain of CBP.A Method for Systematic Assessment of Intrinsically Disordered Protein Regions by NMR.Interplay between minor and major groove-binding transcription factors Sox2 and Oct1 in translocation on DNA studied by paramagnetic and diamagnetic NMR.Single-molecule experiments reveal the flexibility of a Per-ARNT-Sim domain and the kinetic partitioning in the unfolding pathway under force.Nanomechanical stimulus accelerates and directs the self-assembly of silk-elastin-like nanofibers.Mechanical control of the directional stepping dynamics of the kinesin motor.Experimental and computational examination of anastellin (FnIII1c)-polymer interactions.Electrostatically accelerated coupled binding and folding of intrinsically disordered proteinsRole of non-native electrostatic interactions in the coupled folding and binding of PUMA with Mcl-1
P2860
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P2860
Fly-casting in protein-DNA binding: frustration between protein folding and electrostatics facilitates target recognition.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Fly-casting in protein-DNA bin ...... acilitates target recognition.
@en
Fly-casting in protein-DNA bin ...... acilitates target recognition.
@nl
type
label
Fly-casting in protein-DNA bin ...... acilitates target recognition.
@en
Fly-casting in protein-DNA bin ...... acilitates target recognition.
@nl
prefLabel
Fly-casting in protein-DNA bin ...... acilitates target recognition.
@en
Fly-casting in protein-DNA bin ...... acilitates target recognition.
@nl
P356
P1476
Fly-casting in protein-DNA bin ...... acilitates target recognition.
@en
P2093
Yaakov Levy
P304
P356
10.1021/JA065531N
P407
P577
2007-01-01T00:00:00Z