Lysophosphatidic acid, a novel lipid growth factor for human thyroid cells: over-expression of the high-affinity receptor edg4 in differentiated thyroid cancer. - Wikidata - awgldk - TriplyDB

Lysophosphatidic acid, a novel lipid growth factor for human thyroid cells: over-expression of the high-affinity receptor edg4 in differentiated thyroid cancer.

Lysophosphatidic acid, a novel lipid growth factor for human thyroid cells: over-expression of the high-affinity receptor edg4 in differentiated thyroid cancer.

http://www.wikidata.org/entity/Q43567318

about

NHERF2 specifically interacts with LPA2 receptor and defines the specificity and efficiency of receptor-mediated phospholipase C-beta3 activation Over-expression of lysophosphatidic acid receptor-2 in human invasive ductal carcinoma Recent advances in targeting the autotaxin-lysophosphatidate-lipid phosphate phosphatase axis in vivo Negative regulation of cell motile and invasive activities by lysophosphatidic acid receptor-3 in colon cancer HCT116 cells.The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases Insights into the pharmacological relevance of lysophospholipid receptors.Transgenic Expression of Human Lysophosphatidic Acid Receptor LPA2 in Mouse Intestinal Epithelial Cells Induces Intestinal Dysplasia.Phospholipids as cancer biomarkers: Mass spectrometry-based analysis.Lysophosphatidic acid activates lipogenic pathways and de novo lipid synthesis in ovarian cancer cells.Expression of lysophosphatidic acid receptors and local invasiveness and metastasis in Chinese pancreatic cancers.Lysophosphatidic Acid Up-Regulates Hexokinase II and Glycolysis to Promote Proliferation of Ovarian Cancer Cells Inhibition of lysophosphatidic acid receptor-2 expression by RNA interference decreases lysophosphatidic acid-induced urokinase plasminogen activator activation, cell invasion, and migration in ovarian cancer SKOV-3 cells.Sphingosine kinase 1 is upregulated with lysophosphatidic acid receptor 2 in human colorectal cancer.Targeting lysophosphatidic acid receptor type 1 with Debio 0719 inhibits spontaneous metastasis dissemination of breast cancer cells independently of cell proliferation and angiogenesis.Tetracyclines increase lipid phosphate phosphatase expression on plasma membranes and turnover of plasma lysophosphatidate.Transcriptional and post-transcriptional mechanisms for lysophosphatidic acid-induced cyclooxygenase-2 expression in ovarian cancer cells.TRIP6 antagonizes the recruitment of A20 and CYLD to TRAF6 to promote the LPA2 receptor-mediated TRAF6 activation.Regulation of the LPA2 receptor signaling through the carboxyl-terminal tail-mediated protein-protein interactions Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells Evaluating dual activity LPA receptor pan-antagonist/autotaxin inhibitors as anti-cancer agents in vivo using engineered human tumors Lysophosphatidic acid (LPA) and endothelial differentiation gene (Edg) receptors in human pancreatic cancer.Genetic and epigenetic alterations of lysophosphatidic Acid receptor genes in rodent tumors by experimental models Diverse effects of LPA receptors on cell motile activities of cancer cells.Lysophosphatidic acid induces both EGFR-dependent and EGFR-independent effects on DNA synthesis and migration in pancreatic and colorectal carcinoma cells.Different effects on cell proliferation and migration abilities of endothelial cells by LPA₁ and LPA₃ in mammary tumor FM3A cells.Lysophosphatidic acid receptor-3 increases tumorigenicity and aggressiveness of rat hepatoma RH7777 cells.No Involvement of Lysophosphatidic Acid Receptor-3 in Cell Migration of Mouse Lung Tumor Cells Stimulatedby 12-O-Tetradecanoylphorbol-13-acetate Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid.Lysophosphatidic acid transactivates both c-Met and epidermal growth factor receptor, and induces cyclooxygenase-2 expression in human colon cancer LoVo cells.Role of p38 mitogen-activated kinase and c-Jun terminal kinase in migration response to lysophosphatidic acid and sphingosine-1-phosphate in glioma cells.Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer.Identification of genes down-regulated during melanoma progression: a cDNA array study.Lysophosphatidic acid prevents apoptosis of Caco-2 colon cancer cells via activation of mitogen-activated protein kinase and phosphorylation of Bad.LPA2 receptor mediates mitogenic signals in human colon cancer cells.

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P2860

Lysophosphatidic acid, a novel lipid growth factor for human thyroid cells: over-expression of the high-affinity receptor edg4 in differentiated thyroid cancer.

http://www.wikidata.org/entity/Q43567318

description

2001 nî lūn-bûn

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2001年の論文

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年學術文章

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2001年學術文章

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name

Lysophosphatidic acid, a novel ...... differentiated thyroid cancer.

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Lysophosphatidic acid, a novel ...... differentiated thyroid cancer.

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Lysophosphatidic acid, a novel ...... differentiated thyroid cancer.

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Lysophosphatidic acid, a novel ...... differentiated thyroid cancer.

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1097-0215(200102)9999:9999%3C::AID-IJC1166%3E3.0.CO;2-D

P1433

International Journal of Cancer

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Lysophosphatidic acid, a novel ...... differentiated thyroid cancer.

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A Beyer

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H D Röher

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K Köhrer

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S Oberhäuser

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P2860

EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue

Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway

Molecular cloning of the human Edg2 protein and its identification as a functional cellular receptor for lysophosphatidic acid

Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1

Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid

Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex

A single receptor encoded by vzg-1/lpA1/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Genomic characterization of the lysophosphatidic acid receptor gene, lp(A2)/Edg4, and identification of a frameshift mutation in a previously characterized cDNA

The human calcium-independent phospholipase A2 gene multiple enzymes with distinct properties from a single gene

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249-256

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2

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11291053

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