Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase-deficient mice.
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Golgi phosphoprotein 3 determines cell binding properties under dynamic flow by controlling Golgi localization of core 2 N-acetylglucosaminyltransferase 1.N-glycans of core2 beta(1,6)-N-acetylglucosaminyltransferase-I (C2GnT-I) but not those of alpha(1,3)-fucosyltransferase-VII (FucT-VII) are required for the synthesis of functional P-selectin glycoprotein ligand-1 (PSGL-1): effects on P-, L- and E-seTargeting selectins and selectin ligands in inflammation and cancerLeukocyte ligands for endothelial selectins: specialized glycoconjugates that mediate rolling and signaling under flowFunctional analysis of the combined role of the O-linked branching enzyme core 2 beta1-6-N-glucosaminyltransferase and dimerization of P-selectin glycoprotein ligand-1 in rolling on P-selectinGlycosyltransferase-programmed stereosubstitution (GPS) to create HCELL: engineering a roadmap for cell migrationTransfection of antisense core 2 beta1,6-N-acetylglucosaminyltransferase-1 cDNA suppresses selectin ligand expression and tissue infiltration of B-cell precursor leukemia cells'Slings' enable neutrophil rolling at high shearSialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation.P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow.Neutrophil rolling at high shear: flattening, catch bond behavior, tethers and slingsIntravital multiphoton imaging of mouse tibialis anterior muscle.Spleen tyrosine kinase Syk is critical for sustained leukocyte adhesion during inflammation in vivo.The high affinity selectin glycan ligand C2-O-sLex and mRNA transcripts of the core 2 beta-1,6-N-acetylglucosaminyltransferase (C2GnT1) gene are highly expressed in human colorectal adenocarcinomas.Fluorinated per-acetylated GalNAc metabolically alters glycan structures on leukocyte PSGL-1 and reduces cell binding to selectins.C2-O-sLeX glycoproteins are E-selectin ligands that regulate invasion of human colon and hepatic carcinoma cells.Tyrosine sulfation of native mouse Psgl-1 is required for optimal leukocyte rolling on P-selectin in vivo.Core 1-derived O-glycans are essential E-selectin ligands on neutrophils.RAGE and ICAM-1 differentially control leukocyte recruitment during acute inflammation in a stimulus-dependent manner.Biomechanics of leukocyte rollingDifferential regulation of human and murine P-selectin expression and function in vivo.Regulation and migratory role of P-selectin ligands during intestinal inflammation.Heterogeneity of endothelial cells from different organ sites in T-cell subset recruitment.Coordinated roles of ST3Gal-VI and ST3Gal-IV sialyltransferases in the synthesis of selectin ligands.VEGF expression by mesenchymal stem cells contributes to angiogenesis in pancreatic carcinoma.Core2 1-6-N-glucosaminyltransferase-I is crucial for the formation of atherosclerotic lesions in apolipoprotein E-deficient micePSGL-1 from the murine leukocytic cell line WEHI-3 is enriched for core 2-based O-glycans with sialyl Lewis x antigenGlycosylation in immune cell trafficking.Pathobiology of colorectal cancer hepatic metastases with an emphasis on prognostic factors.The expanding role of α2-3 sialylation for leukocyte trafficking in vivo.Endothelial heterogeneity and adhesion molecules N-glycosylation: implications in leukocyte trafficking in inflammation.Quantitative dynamic footprinting microscopy.X-ray crystal structure of leukocyte type core 2 beta1,6-N-acetylglucosaminyltransferase. Evidence for a convergence of metal ion-independent glycosyltransferase mechanism.L- and P-selectins collaborate to support leukocyte rolling in vivo when high-affinity P-selectin-P-selectin glycoprotein ligand-1 interaction is inhibited.What Have We Learned from Glycosyltransferase Knockouts in Mice?Epigenetic modification of the PD-1 (Pdcd1) promoter in effector CD4(+) T cells tolerized by peptide immunotherapy.A crucial role for T-bet in selectin ligand expression in T helper 1 (Th1) cells.Core2 1-6-N-glucosaminyltransferase-I deficiency protects injured arteries from neointima formation in ApoE-deficient mice.CXCL1-triggered interaction of LFA1 and ICAM1 control glucose-induced leukocyte recruitment during inflammation in vivo.Quercetin supplementation and its effect on human monocyte gene expression profiles in vivo.
P2860
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P2860
Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase-deficient mice.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Severe impairment of leukocyte ...... nyltransferase-deficient mice.
@en
Severe impairment of leukocyte ...... nyltransferase-deficient mice.
@nl
type
label
Severe impairment of leukocyte ...... nyltransferase-deficient mice.
@en
Severe impairment of leukocyte ...... nyltransferase-deficient mice.
@nl
prefLabel
Severe impairment of leukocyte ...... nyltransferase-deficient mice.
@en
Severe impairment of leukocyte ...... nyltransferase-deficient mice.
@nl
P2093
P1433
P1476
Severe impairment of leukocyte ...... nyltransferase-deficient mice.
@en
P2093
P304
P356
10.1182/BLOOD.V97.12.3812
P407
P577
2001-06-01T00:00:00Z