Importance of peptide amino and carboxyl termini to the stability of MHC class I molecules.
about
An N-acetylated natural ligand of human histocompatibility leukocyte antigen (HLA)-B39. Classical major histocompatibility complex class I proteins bind peptides with a blocked NH(2) terminus in vivoBiochemical characterization and crystalization of human Zn-alpha2-glycoprotein, a soluble class I major histocompatibility complex homologPoor binding of a HER-2/neu epitope (GP2) to HLA-A2.1 is due to a lack of interactions with the center of the peptideThe structural basis for the increased immunogenicity of two HIV-reverse transcriptase peptide variant/class I major histocompatibility complexesClass I major histocompatibility complex anchor substitutions alter the conformation of T cell receptor contactsAlternate interactions define the binding of peptides to the MHC molecule IA(b).Structural analysis of mycobacterial and murine hsp60 epitopes in complex with the class I MHC molecule H-2DbThermodynamic and structural analysis of peptide- and allele-dependent properties of two HLA-B27 subtypes exhibiting differential disease associationStructures of MART-126/27–35 Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell RecognitionPhosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed selfCrystal Structures of HLA-A*0201 Complexed with Melan-A/MART-1 26(27L)-35 Peptidomimetics Reveal Conformational Heterogeneity and Highlight Degeneracy of T Cell RecognitionCross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive IndividualsCrystal structures of HLA-A*0201 complexed with antigenic peptides with either the amino- or carboxyl-terminal group substituted by a methyl groupInflammation-associated nitrotyrosination affects TCR recognition through reduced stability and alteration of the molecular surface of the MHC complexFunctional analysis of amino acid residues encompassing and surrounding two neighboring H-2Db-restricted cytotoxic T-lymphocyte epitopes in simian virus 40 tumor antigen.Major histocompatibility complex class I molecules bind natural peptide ligands lacking the amino-terminal binding residue in vivo.An endogenous HIV envelope-derived peptide without the terminal NH3+ group anchor is physiologically presented by major histocompatibility complex class I molecules.New synthetic non-peptide ligands for classical major histocompatibility complex class I molecules.Predicting peptides binding to MHC class II molecules using multi-objective evolutionary algorithmsCrystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides.Mechanisms of antigen presentation.Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens.Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K(d) that stimulates CD8 T cells in insulin-dependent diabetes mellitusThe endoplasmic reticulum lumenal domain of the adenovirus type 2 E3-19K protein binds to peptide-filled and peptide-deficient HLA-A*1101 molecules.Development of a novel in silico docking simulation model for the fine HIV-1 cytotoxic T lymphocyte epitope mapping.Expression of the mouse MHC class Ib H2-T11 gene product, a paralog of H2-T23 (Qa-1) with shared peptide-binding specificity.Binding interactions between peptides and proteins of the class II major histocompatibility complex.Noncanonical peptides in complex with MHC class I.The Carboxy Terminus of the Ligand Peptide Determines the Stability of the MHC Class I Molecule H-2Kb: A Combined Molecular Dynamics and Experimental Study.Invariant chain protects class II histocompatibility antigens from binding intact polypeptides in the endoplasmic reticulum.Specificity of the H-2 L(d)-restricted cytotoxic T-lymphocyte response to the mouse hepatitis virus nucleocapsid proteinDistortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer PeptideTapasin and other chaperones: models of the MHC class I loading complex.Stability of empty and peptide-loaded class II major histocompatibility complex molecules at neutral and endosomal pH: comparison to class I proteins.The recognition of the nonclassical major histocompatibility complex (MHC) class I molecule, T10, by the gammadelta T cell, G8.Alteration of a single hydrogen bond between class II molecules and peptide results in rapid degradation of class II molecules after invariant chain removal.Transporters associated with antigen processing (TAP)-independent presentation of soluble insulin to alpha/beta T cells by the class Ib gene product, Qa-1(b).Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptideTolerance to amino acid variations in peptides binding to the major histocompatibility complex class I protein H-2Kb.Secondary anchor substitutions in an HLA-A*0201-restricted T-cell epitope derived from Her-2/neu.
P2860
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P2860
Importance of peptide amino and carboxyl termini to the stability of MHC class I molecules.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
Importance of peptide amino an ...... lity of MHC class I molecules.
@en
Importance of peptide amino an ...... lity of MHC class I molecules.
@nl
type
label
Importance of peptide amino an ...... lity of MHC class I molecules.
@en
Importance of peptide amino an ...... lity of MHC class I molecules.
@nl
prefLabel
Importance of peptide amino an ...... lity of MHC class I molecules.
@en
Importance of peptide amino an ...... lity of MHC class I molecules.
@nl
P356
P1433
P1476
Importance of peptide amino an ...... lity of MHC class I molecules.
@en
P2093
P304
P356
10.1126/SCIENCE.8023162
P407
P577
1994-07-01T00:00:00Z