Alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons.
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Synphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by alpha-synucleinPhysicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)Targeting heat shock proteins to modulate α-synuclein toxicityProtein degradation pathways in Parkinson's disease: curse or blessingNiclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition14-3-3 protein targets misfolded chaperone-associated proteins to aggresomesC-Terminal Tyrosine Residue Modifications Modulate the Protective Phosphorylation of Serine 129 of α-Synuclein in a Yeast Model of Parkinson's Disease.Association of the cytoskeletal GTP-binding protein Sept4/H5 with cytoplasmic inclusions found in Parkinson's disease and other synucleinopathiesSirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's diseaseFormation of toxic oligomeric alpha-synuclein species in living cellsalpha-Synuclein produces a long-lasting increase in neurotransmitter releaseRevisiting and revising the purinosomeAssessing the subcellular dynamics of alpha-synuclein using photoactivation microscopy.A Novel Microfluidic Cell Co-culture Platform for the Study of the Molecular Mechanisms of Parkinson's Disease and Other SynucleinopathiesAn scFv intrabody against the nonamyloid component of alpha-synuclein reduces intracellular aggregation and toxicityDopamine-induced conformational changes in alpha-synucleinIn vivo imaging of alpha-synuclein in mouse cortex demonstrates stable expression and differential subcellular compartment mobility.Synphilin-1 enhances α-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent mannerLysosomal function in macromolecular homeostasis and bioenergetics in Parkinson's disease.A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration.Tau enhances α-synuclein aggregation and toxicity in cellular models of synucleinopathy.Transmission electron microscopy characterization of fluorescently labelled amyloid β 1-40 and α-synuclein aggregatesDifferential effects of UCHL1 modulation on alpha-synuclein in PD-like models of alpha-synucleinopathy.Quantitative analysis of α-synuclein solubility in living cells using split GFP complementationAmyloid fibrillation of insulin under water-limited conditionsMolecular chaperone dysfunction in neurodegenerative diseases and effects of curcumin.ER stress response plays an important role in aggregation of α-synucleinPharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases.Development and screening of contrast agents for in vivo imaging of Parkinson's disease.Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies.Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation.NADH fluorescence lifetime is an endogenous reporter of α-synuclein aggregation in live cellsSmall Molecules Detected by Second-Harmonic Generation Modulate the Conformation of Monomeric α-Synuclein and Reduce Its Aggregation in CellsAutophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment.Chemical induction of Hsp70 reduces α-synuclein aggregation in neuroglioma cells.shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity.Alpha-synuclein aggregation involves a bafilomycin A 1-sensitive autophagy pathway.Bifunctional Anti-Non-Amyloid Component α-Synuclein Nanobodies Are Protective In Situ.Neurodegenerative disorders: Parkinson's disease and Huntington's diseaseThe mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease.
P2860
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P2860
Alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Alpha-synuclein-enhanced green ...... inclusions in primary neurons.
@en
Alpha-synuclein-enhanced green ...... inclusions in primary neurons.
@nl
type
label
Alpha-synuclein-enhanced green ...... inclusions in primary neurons.
@en
Alpha-synuclein-enhanced green ...... inclusions in primary neurons.
@nl
prefLabel
Alpha-synuclein-enhanced green ...... inclusions in primary neurons.
@en
Alpha-synuclein-enhanced green ...... inclusions in primary neurons.
@nl
P2093
P1433
P1476
Alpha-synuclein-enhanced green ...... inclusions in primary neurons.
@en
P2093
P304
P356
10.1016/S0306-4522(01)00113-0
P407
P577
2001-01-01T00:00:00Z