Identification and functional characterization of eight CYP3A4 protein variants.
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Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: implications for drug therapyCYP3A4 and CYP3A5 genotyping by PyrosequencingFunctionally defective or altered CYP3A4 and CYP3A5 single nucleotide polymorphisms and their detection with genotyping testsSequence diversity and haplotype structure at the human CYP3A clusterComparison of the inhibitory profiles of itraconazole and cimetidine in cytochrome P450 3A4 genetic variantsGenetic polymorphisms in MDR1, CYP3A4 and CYP3A5 genes in a Ghanaian population: a plausible explanation for altered metabolism of ivermectin in humans?Comparative analysis of response to selection with three insecticides in the dengue mosquito Aedes aegypti using mRNA sequencingInfluence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide.Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin.Reduced methylprednisolone clearance causing prolonged pharmacodynamics in a healthy subject was not associated with CYP3A5*3 allele or a change in diet composition.Clinical application of pharmacogenomics.Fatal methadone toxicity: potential role of CYP3A4 genetic polymorphism.Pharmacogenetics in diverse ethnic populations--implications for drug discovery and development.Frequency of genetic polymorphisms of PXR gene in the Brazilian population.Genetic polymorphisms of cytochrome P450 enzymes and the effect on interindividual, pharmacokinetic variability in extensive metabolizers.Polymorphic Variants of SCN1A and EPHX1 Influence Plasma Carbamazepine Concentration, Metabolism and Pharmacoresistance in a Population of Kosovar Albanian Epileptic PatientsDifferences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms.Impact of inter-individual differences in drug metabolism and pharmacokinetics on safety evaluation.Sarcomas and pharmacogenetics.Overview of the pharmacogenetics of HIV therapy.Clinical implications of CYP3A polymorphisms.Characterization of the genetic variation present in CYP3A4 in three South African populations.Methadone-associated long QT syndrome: improving pharmacotherapy for dependence on illegal opioids and lessons learned for pharmacology.Effects of genetic polymorphism of cytochrome P450 enzymes on the pharmacokinetics of benzodiazepines.Pharmacogenetics of the constitutive androstane receptor.Interindividual variability of methadone response: impact of genetic polymorphism.Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa.The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism.Pharmacogenomics of CYP3A: considerations for HIV treatment.The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy.Gender and interindividual variability in pharmacokinetics.Structural basis for regiospecific midazolam oxidation by human cytochrome P450 3A4.Pharmacogenetics in American Indian populations: analysis of CYP2D6, CYP3A4, CYP3A5, and CYP2C9 in the Confederated Salish and Kootenai Tribes.An update on ethnic differences in drug metabolism and toxicity from anti-cancer drugs.Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.Interplay of pharmacogenetic variations in ABCB1 transporters and cytochrome P450 enzymes.CYP3A4*22: promising newly identified CYP3A4 variant allele for personalizing pharmacotherapy.Irreversible hepatotoxicity after administration of trabectedin to a pleiomorphic sarcoma patient with a rare ABCC2 polymorphism: a case report.Functional gene variants of CYP3A4.CYP3A4 and MDR1 alleles in a Portuguese population.
P2860
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P2860
Identification and functional characterization of eight CYP3A4 protein variants.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Identification and functional characterization of eight CYP3A4 protein variants.
@en
Identification and functional characterization of eight CYP3A4 protein variants.
@nl
type
label
Identification and functional characterization of eight CYP3A4 protein variants.
@en
Identification and functional characterization of eight CYP3A4 protein variants.
@nl
prefLabel
Identification and functional characterization of eight CYP3A4 protein variants.
@en
Identification and functional characterization of eight CYP3A4 protein variants.
@nl
P2093
P1476
Identification and functional characterization of eight CYP3A4 protein variants.
@en
P2093
Brockmoller J
Domanski TL
Halpert JR
P304
P356
10.1097/00008571-200107000-00008
P577
2001-07-01T00:00:00Z