Genomic landscape of transcriptional and epigenetic dysregulation in early onset polyglutamine disease.
about
Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph DiseaseMolecular targets of chromatin repressive mark H3K9me3 in primate progenitor cells within adult neurogenic niches.Transcription, epigenetics and ameliorative strategies in Huntington's Disease: a genome-wide perspectiveComponents of the endocannabinoid and dopamine systems are dysregulated in Huntington's disease: analysis of publicly available microarray datasets.A standardized autopsy procurement allows for the comprehensive study of DIPG biology.The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's DiseaseNeonatal Iron Supplementation Induces Striatal Atrophy in Female YAC128 Huntington's Disease Mice.Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced NeurotoxicityAn Intrabody Drug (rAAV6-INT41) Reduces the Binding of N-Terminal Huntingtin Fragment(s) to DNA to Basal Levels in PC12 Cells and Delays Cognitive Loss in the R6/2 Animal ModelContribution of Neuroepigenetics to Huntington's Disease.Altered enhancer transcription underlies Huntington's disease striatal transcriptional signatureNeuroprotective effects of psychotropic drugs in Huntington's diseaseInvolvement of HDAC1 and HDAC3 in the Pathology of Polyglutamine Disorders: Therapeutic Implications for Selective HDAC1/HDAC3 Inhibitors.A link between chromatin condensation mechanisms and Huntington's disease: connecting the dots.Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease.A Drosophila model of Huntington disease-like 2 exhibits nuclear toxicity and distinct pathogenic mechanisms from Huntington disease.Understanding histone deacetylation in Huntington's diseaseNeuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.Epigenetic modifications as novel therapeutic targets for Huntington's disease.Neuronal Deletion of Kmt2a/Mll1 Histone Methyltransferase in Ventral Striatum is Associated with Defective Spike-Timing-Dependent Striatal Synaptic Plasticity, Altered Response to Dopaminergic Drugs, and Increased Anxiety.Comparison of spinocerebellar ataxia type 3 mouse models identifies early gain-of-function, cell-autonomous transcriptional changes in oligodendrocytes.Epigenetics of Huntington's Disease.Early alteration of epigenetic-related transcription in Huntington's disease mouse models.The role of Twist1 in mutant huntingtin-induced transcriptional alterations and neurotoxicity
P2860
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P2860
Genomic landscape of transcriptional and epigenetic dysregulation in early onset polyglutamine disease.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Genomic landscape of transcrip ...... y onset polyglutamine disease.
@en
Genomic landscape of transcrip ...... y onset polyglutamine disease.
@nl
type
label
Genomic landscape of transcrip ...... y onset polyglutamine disease.
@en
Genomic landscape of transcrip ...... y onset polyglutamine disease.
@nl
prefLabel
Genomic landscape of transcrip ...... y onset polyglutamine disease.
@en
Genomic landscape of transcrip ...... y onset polyglutamine disease.
@nl
P1476
Genomic landscape of transcrip ...... ly onset polyglutamine disease
@en
P2093
Deisy Guiretti
Jose P Lopez-Atalaya
P304
10471-10482
P356
10.1523/JNEUROSCI.0670-13.2013
P407
P577
2013-06-01T00:00:00Z