Bystander effect of purine nucleoside analogues in HSV-1 tk suicide gene therapy is superior to that of pyrimidine nucleoside analogues.
about
Prodrugs for Gene-Directed Enzyme-Prodrug Therapy (Suicide Gene Therapy)Expression of thymidine kinase mediated by a novel non-viral delivery system under the control of vascular endothelial growth factor receptor 2 promoter selectively kills human umbilical vein endothelial cells.Guanosine analogues as anti-herpesvirus agents.Prodrug activation enzymes in cancer gene therapy.Gene directed enzyme/prodrug therapy of cancer: historical appraisal and future prospectives.Acyclic/carbocyclic guanosine analogues as anti-herpesvirus agents.Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues.C-5 hydroxyethyl and hydroxypropyl acyclonucleosides as substrates for thymidine kinase of herpes simplex virus type 1 (HSV-1 TK): syntheses and biological evaluation.Characterisation of enzyme prodrug gene therapy combinations in coated spheroids and vascular networks in vitro.Enhanced toxicity of purine nucleoside analogs in cells expressing Drosophila melanogaster nucleoside kinase mutants.Transfectant mosaic spheroids: a new model for evaluation of tumour cell killing in targeted radiotherapy and experimental gene therapy.Development of synthetic promoters for radiation-mediated gene therapy.Ultrasound microbubble contrast agent-mediated suicide gene transfection in the treatment of hepatic cancer.Characterization of herpes simplex virus type 1 thymidine kinase mutants selected under a single round of high-dose brivudinLocalized adenovirus gene delivery using antiviral IgG complexation.Selection of HSV-1 TK gene-transfected murine mammary carcinoma cells resistant to (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and ganciclovir (GCV).Active site mutants of Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.Functional expression of thymidine kinase in human leukaemic and colorectal cells, delivered as EGFP fusion protein by herpesvirus saimiri-based vector.
P2860
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P2860
Bystander effect of purine nucleoside analogues in HSV-1 tk suicide gene therapy is superior to that of pyrimidine nucleoside analogues.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Bystander effect of purine nuc ...... rimidine nucleoside analogues.
@en
Bystander effect of purine nuc ...... rimidine nucleoside analogues.
@nl
type
label
Bystander effect of purine nuc ...... rimidine nucleoside analogues.
@en
Bystander effect of purine nuc ...... rimidine nucleoside analogues.
@nl
prefLabel
Bystander effect of purine nuc ...... rimidine nucleoside analogues.
@en
Bystander effect of purine nuc ...... rimidine nucleoside analogues.
@nl
P2093
P2860
P356
P1433
P1476
Bystander effect of purine nuc ...... rimidine nucleoside analogues.
@en
P2093
Balzarini J
De Clercq E
P2860
P2888
P304
P356
10.1038/SJ.GT.3300806
P577
1999-02-01T00:00:00Z
P5875
P6179
1028363954