How is a metabolic intermediate formed in the mechanism-based inactivation of cytochrome P450 by using 1,1-dimethylhydrazine: hydrogen abstraction or nitrogen oxidation?
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Dichotomous hydrogen atom transfer vs proton-coupled electron transfer during activation of X-H bonds (X = C, N, O) by nonheme iron-oxo complexes of variable basicitySuicide Inhibition of Cytochrome P450 Enzymes by Cyclopropylamines via a Ring-Opening Mechanism: Proton-Coupled Electron Transfer Makes a Difference.Applications of density functional theory to iron-containing molecules of bioinorganic interest.Importance of H-abstraction in the final step of nitrosoalkane formation in the mechanism-based inactivation of cytochrome P450 by amine-containing drugsTheoretical insights into the reductive metabolism of CCl4 by cytochrome P450 enzymes and the CCl4-dependent suicidal inactivation of P450.Bio-activation of 4-alkyl analogs of 1,4-dihydropyridine mediated by cytochrome P450 enzymes.
P2860
How is a metabolic intermediate formed in the mechanism-based inactivation of cytochrome P450 by using 1,1-dimethylhydrazine: hydrogen abstraction or nitrogen oxidation?
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How is a metabolic intermediat ...... raction or nitrogen oxidation?
@en
How is a metabolic intermediat ...... raction or nitrogen oxidation?
@nl
type
label
How is a metabolic intermediat ...... raction or nitrogen oxidation?
@en
How is a metabolic intermediat ...... raction or nitrogen oxidation?
@nl
prefLabel
How is a metabolic intermediat ...... raction or nitrogen oxidation?
@en
How is a metabolic intermediat ...... raction or nitrogen oxidation?
@nl
P2093
P2860
P356
P1476
How is a metabolic intermediat ...... raction or nitrogen oxidation?
@en
P2093
Hajime Hirao
Pratanphorn Chuanprasit
Xiaoqing Wang
Ying Yi Cheong
P2860
P304
P356
10.1002/CHEM.201300689
P407
P577
2013-04-16T00:00:00Z