Early intervention with high-dose acyclovir treatment during primary herpes simplex virus infection reduces latency and subsequent reactivation in the nervous system in vivo.
about
Herpes simplex virus and the lexicon of latency and reactivation: a call for defining terms and building an integrated collective frameworkDe novo synthesis of VP16 coordinates the exit from HSV latency in vivo.Recurrent vaginal shedding of herpes simplex type 2 virus in the mouse and effects of antiviral therapy.Recent progress in herpes simplex virus immunobiology and vaccine researchHerpes simplex virus DNA synthesis is not a decisive regulatory event in the initiation of lytic viral protein expression in neurons in vivo during primary infection or reactivation from latency.In vivo reactivation of latent herpes simplex virus 1 in mice can occur in the brain before occurring in the trigeminal ganglionEffects of herpes simplex virus type 2 glycoprotein vaccines and CLDC adjuvant on genital herpes infection in the guinea pig.CMX001 potentiates the efficacy of acyclovir in herpes simplex virus infectionsImmunization with a vaccine combining herpes simplex virus 2 (HSV-2) glycoprotein C (gC) and gD subunits improves the protection of dorsal root ganglia in mice and reduces the frequency of recurrent vaginal shedding of HSV-2 DNA in guinea pigs compaCross-presentation and genome-wide screening reveal candidate T cells antigens for a herpes simplex virus type 1 vaccine.A Dual-Modality Herpes Simplex Virus 2 Vaccine for Preventing Genital Herpes by Using Glycoprotein C and D Subunit Antigens To Induce Potent Antibody Responses and Adenovirus Vectors Containing Capsid and Tegument Proteins as T Cell ImmunogensImmunization with a replication-defective herpes simplex virus 2 mutant reduces herpes simplex virus 1 infection and prevents ocular disease.A CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates.Glycoprotein D adjuvant herpes simplex virus vaccine.The number of herpes simplex virus-infected neurons and the number of viral genome copies per neuron correlate with the latent viral load in gangliaPsychological stress exacerbates primary vaginal herpes simplex virus type 1 (HSV-1) infection by impairing both innate and adaptive immune responses.Vaxfectin-adjuvanted plasmid DNA vaccine improves protection and immunogenicity in a murine model of genital herpes infectionImpairment in reactivation of a latency associated transcript (LAT)-deficient HSV-2 is not solely dependent on the latent viral load or the number of CD8(+) T cells infiltrating the ganglia.Immunization with HSV-1 glycoprotein C prevents immune evasion from complement and enhances the efficacy of an HSV-1 glycoprotein D subunit vaccineProtection provided by a herpes simplex virus 2 (HSV-2) glycoprotein C and D subunit antigen vaccine against genital HSV-2 infection in HSV-1-seropositive guinea pigs.Helicase-primase as a target of new therapies for herpes simplex virus infections.Evidence that the herpes simplex virus type 1 ICP0 protein does not initiate reactivation from latency in vivo.Quantitative analysis of herpes simplex virus reactivation in vivo demonstrates that reactivation in the nervous system is not inhibited at early times postinoculationAnalysis of herpes simplex virus ICP0 promoter function in sensory neurons during acute infection, establishment of latency, and reactivation in vivo.Analysis of Herpes Simplex Virus Reactivation in Explant Reveals a Method-Dependent Difference in Measured Timing of Reactivation.Efficacy of N-methanocarbathymidine against genital herpes simplex virus type 2 shedding and infection in guinea pigs.Effects of antiviral medications on herpetic epithelial keratitis in mice.Virological and molecular biological evidence supporting herpes simplex virus type 1 corneal latency.Randomized double-blinded, placebo-controlled clinical trial of famciclovir for reduction of Ménière's disease symptoms.Effects of anti herpetic drugs on mice with herpetic epithelial keratitis after reactivation of herpes simplex virus type 1.Cyclooxygenase (COX)-inhibiting drug reduces HSV-1 reactivation in the mouse eye model.Compartmented neuronal cultures reveal two distinct mechanisms for alpha herpesvirus escape from genome silencing.
P2860
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P2860
Early intervention with high-dose acyclovir treatment during primary herpes simplex virus infection reduces latency and subsequent reactivation in the nervous system in vivo.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Early intervention with high-d ...... in the nervous system in vivo.
@en
Early intervention with high-d ...... in the nervous system in vivo.
@nl
type
label
Early intervention with high-d ...... in the nervous system in vivo.
@en
Early intervention with high-d ...... in the nervous system in vivo.
@nl
prefLabel
Early intervention with high-d ...... in the nervous system in vivo.
@en
Early intervention with high-d ...... in the nervous system in vivo.
@nl
P2093
P356
P1476
Early intervention with high-d ...... in the nervous system in vivo
@en
P2093
Bernstein DI
Sawtell NM
Stanberry LR
P304
P356
10.1086/323551
P407
P577
2001-09-10T00:00:00Z