about
Herpes simplex virus and the lexicon of latency and reactivation: a call for defining terms and building an integrated collective frameworkDe novo synthesis of VP16 coordinates the exit from HSV latency in vivo.A forward phenotypically driven unbiased genetic analysis of host genes that moderate herpes simplex virus virulence and stromal keratitis in mice.Therapeutic implications of new insights into the critical role of VP16 in initiating the earliest stages of HSV reactivation from latency.De Novo Herpes Simplex Virus VP16 Expression Gates a Dynamic Programmatic Transition and Sets the Latent/Lytic Balance during Acute Infection in Trigeminal Ganglia.Herpes simplex virus mutant generation and dual-detection methods for gaining insight into latent/lytic cycles in vivo.The herpes simplex virus type 1 latency associated transcript locus is required for the maintenance of reactivation competent latent infections.Early intervention with high-dose acyclovir treatment during primary herpes simplex virus infection reduces latency and subsequent reactivation in the nervous system in vivo.Inferred father-to-son transmission of herpes simplex virus results in near-perfect preservation of viral genome identity and in vivo phenotypes.Resolution of herpes simplex virus reactivation in vivo results in neuronal destruction
P50
Q28066711-1AD0A828-5DCC-45F3-A873-52B121208C57Q33422983-B3AE98F8-7FC7-430C-BE71-9B6ADE3280CCQ35126625-B1C368C8-6694-4516-A71B-E7F41538693DQ39769235-E616CB83-8272-4258-85F5-86EC8AC48596Q40547302-6566C96C-A99F-4D3E-968D-7428F73E6401Q42222092-F05BA1AA-E120-4297-8721-3358B72D58DDQ42589791-96758981-E922-415A-B824-C61152820F35Q43749186-AF5A1936-B578-4E05-BB63-1A429C144F29Q45325873-26A9EAC6-8682-44D8-95D4-2BBE99390D9EQ90065575-2E3749D9-CCB2-437A-AE65-16B9311EF510
P50
description
onderzoeker
@nl
researcher, ORCID id # 0000-0002-0246-2810
@en
name
Richard L Thompson
@ast
Richard L Thompson
@en
Richard L Thompson
@nl
type
label
Richard L Thompson
@ast
Richard L Thompson
@en
Richard L Thompson
@nl
prefLabel
Richard L Thompson
@ast
Richard L Thompson
@en
Richard L Thompson
@nl
P106
P31
P496
0000-0002-0246-2810