Non-toxic ubiquitous over-expression of utrophin in the mdx mouse.
about
Ets-2 repressor factor silences extrasynaptic utrophin by N-box mediated repression in skeletal muscle.High levels of sarcospan are well tolerated and act as a sarcolemmal stabilizer to address skeletal muscle and pulmonary dysfunction in DMD.Sarcospan-dependent Akt activation is required for utrophin expression and muscle regeneration.Therapeutic approaches to muscular dystrophy.Viral-mediated gene therapy for the muscular dystrophies: successes, limitations and recent advancesInhibition of muscle fibrosis results in increases in both utrophin levels and the number of revertant myofibers in Duchenne muscular dystrophy.Sarcospan: a small protein with large potential for Duchenne muscular dystrophy2015 William Allan Award.Novel compounds for the treatment of Duchenne muscular dystrophy: emerging therapeutic agentsGene therapy in large animal models of muscular dystrophy.Progress in therapy for Duchenne muscular dystrophy.Duchenne muscular dystrophy drug discovery - the application of utrophin promoter activation screening.Advances in genetic therapeutic strategies for Duchenne muscular dystrophy.Second-generation compound for the modulation of utrophin in the therapy of DMD.Thermodynamic stability, unfolding kinetics, and aggregation of the N-terminal actin-binding domains of utrophin and dystrophin.Functional improvement of dystrophic muscle by repression of utrophin: let-7c interaction.Therapy for Duchenne muscular dystrophy: renewed optimism from genetic approaches.ECM-Related Myopathies and Muscular Dystrophies: Pros and Cons of Protein Therapies.
P2860
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P2860
Non-toxic ubiquitous over-expression of utrophin in the mdx mouse.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Non-toxic ubiquitous over-expression of utrophin in the mdx mouse.
@en
Non-toxic ubiquitous over-expression of utrophin in the mdx mouse.
@nl
type
label
Non-toxic ubiquitous over-expression of utrophin in the mdx mouse.
@en
Non-toxic ubiquitous over-expression of utrophin in the mdx mouse.
@nl
prefLabel
Non-toxic ubiquitous over-expression of utrophin in the mdx mouse.
@en
Non-toxic ubiquitous over-expression of utrophin in the mdx mouse.
@nl
P2093
P1476
Non-toxic ubiquitous over-expression of utrophin in the mdx mouse.
@en
P2093
Tinsley JM
Townsend ER
P304
P356
10.1016/S0960-8966(01)00220-6
P577
2001-11-01T00:00:00Z