The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial.
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Translation of TRO40303 from myocardial infarction models to demonstration of safety and tolerance in a randomized Phase I trialInotropic agents and vasodilator strategies for acute myocardial infarction complicated by cardiogenic shock or low cardiac output syndromeRegulation and role of the presynaptic and myocardial Na+/H+ exchanger NHE1: effects on the sympathetic nervous system in heart failureNo reflow phenomenon in percutaneous coronary interventions in ST-segment elevation myocardial infarction9th Hatter Biannual Meeting: position document on ischaemia/reperfusion injury, conditioning and the ten commandments of cardioprotectionMyocardial reperfusion injury: looking beyond primary PCICarbonic anhydrase activation is associated with worsened pathological remodeling in human ischemic diabetic cardiomyopathyMaximum type 1 error rate inflation in multiarmed clinical trials with adaptive interim sample size modificationsSilencing of cardiac mitochondrial NHE1 prevents mitochondrial permeability transition pore opening.Nonantithrombotic medical options in acute coronary syndromes: old agents and new lines on the horizon.Overexpression of the Na+/H+ exchanger and ischemia-reperfusion injury in the myocardium.The effectiveness of antioxidant vitamins C and E in reducing myocardial infarct size in patients subjected to percutaneous coronary angioplasty (PREVEC Trial): study protocol for a pilot randomized double-blind controlled trialNa+/H+ exchangers: physiology and link to hypertension and organ ischemia.Riluzole protects against cardiac ischaemia and reperfusion damage via block of the persistent sodium current.Adjuvant cardioprotection in cardiac surgery: update.Novel therapeutic strategies for ischemic heart diseaseGlycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer questionSuccinate metabolism: a new therapeutic target for myocardial reperfusion injury.NHE isoform switching and KChIP2 upregulation in aging porcine atria.Is timing everything? Therapeutic potential of modulators of cardiac Na(+) transporters.Na(+)/H(+) exchange and hypoxic pulmonary hypertension.Targeting cardiomyocyte Ca2+ homeostasis in heart failure.The cardiac Na-H exchanger: a key downstream mediator for the cellular hypertrophic effects of paracrine, autocrine and hormonal factors.Management of cardiogenic shock due to acute coronary syndromes.Mechanisms, management and future directions for reperfusion injury after acute myocardial infarction.The role of the persistent Na(+) current during cardiac ischemia and hypoxia.Structural and functional analysis of the Na+/H+ exchangerPhysiological role and regulation of the Na+/H+ exchanger.The RSK Inhibitor BIX02565 Limits Cardiac Ischemia/Reperfusion Injury.Chronic inhibition of the Na+/H+ - exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodelling.Pharmacologic therapeutics for cardiac reperfusion injury.The cardiac persistent sodium current: an appealing therapeutic target?Why did the NHE inhibitor clinical trials fail?Effect of atrial natriuretic peptide on left ventricular remodelling in patients with acute myocardial infarction.Cardioprotection and myocardial reperfusion: pitfalls to clinical applicationCariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs--an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research.The diagnosis and treatment of the no-reflow phenomenon in patients with myocardial infarction undergoing percutaneous coronary interventionOrphan targets for reperfusion injury.Ion channels, transporters, and pumps as targets for heart failure therapyLoss of NHE1 activity leads to reduced oxidative stress in heart and mitigates high-fat diet-induced myocardial stress.
P2860
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P2860
The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
The Na(+)/H(+) exchange inhibi ...... ial infarction (ESCAMI) trial.
@en
type
label
The Na(+)/H(+) exchange inhibi ...... ial infarction (ESCAMI) trial.
@en
prefLabel
The Na(+)/H(+) exchange inhibi ...... ial infarction (ESCAMI) trial.
@en
P2093
P1476
The Na(+)/H(+) exchange inhibi ...... ial infarction (ESCAMI) trial.
@en
P2093
ESCAMI Investigators
G Rasmanis
H Suryapranata
J P Monassier
K L Neuhaus
R Schröder
P304
P356
10.1016/S0735-1097(01)01608-4
P407
P577
2001-11-01T00:00:00Z