Skeletal muscle uncoupling-induced longevity in mice is linked to increased substrate metabolism and induction of the endogenous antioxidant defense system.

Skeletal muscle uncoupling-induced longevity in mice is linked to increased substrate metabolism and induction of the endogenous antioxidant defense system.

Item
http://www.wikidata.org/entity/Q43810687
Mitochondrial uncoupling proteins and energy metabolismRole of UCP1 Gene Variants in Interethnic Differences in the Development of Cardio-Metabolic DiseasesActivation of AMPKα2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrityActivation of muscular TrkB by its small molecular agonist 7,8-dihydroxyflavone sex-dependently regulates energy metabolism in diet-induced obese mice.Skeletal muscle mitochondrial uncoupling prevents diabetes but not obesity in NZO mice, a model for polygenic diabesity.The influence of skeletal muscle on systemic aging and lifespan.Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine.Mitochondrial uncoupling reduces exercise capacity despite several skeletal muscle metabolic adaptations.Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action.Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling.Mitochondrial dysfunction and therapeutic approaches in respiratory and limb muscles of cancer cachectic mice.
P2860

Skeletal muscle uncoupling-induced longevity in mice is linked to increased substrate metabolism and induction of the endogenous antioxidant defense system.

Item
http://www.wikidata.org/entity/Q43810687
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
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2012年學術文章
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2012年學術文章
@zh-hant
name
Skeletal muscle uncoupling-ind ...... us antioxidant defense system.
@en
Skeletal muscle uncoupling-ind ...... us antioxidant defense system.
@nl
type
label
Skeletal muscle uncoupling-ind ...... us antioxidant defense system.
@en
Skeletal muscle uncoupling-ind ...... us antioxidant defense system.
@nl
prefLabel
Skeletal muscle uncoupling-ind ...... us antioxidant defense system.
@en
Skeletal muscle uncoupling-ind ...... us antioxidant defense system.
@nl
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Skeletal muscle uncoupling-ind ...... us antioxidant defense system.
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P2093
P2860
P304
P31
P356
10.1152/AJPENDO.00518.2012
P433
P478
P50
P577
P698