Versatile biosynthetic engineering of sialic acid in living cells using synthetic sialic acid analogues.
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Bioorthogonal chemistry: fishing for selectivity in a sea of functionalityStructures of B-Lymphotropic Polyomavirus VP1 in Complex with Oligosaccharide LigandsSialoside analogue arrays for rapid identification of high affinity siglec ligandsIn situ trans ligands of CD22 identified by glycan-protein photocross-linking-enabled proteomics.Metabolism of diazirine-modified N-acetylmannosamine analogues to photo-cross-linking sialosides.Mechanism of uptake and incorporation of the non-human sialic acid N-glycolylneuraminic acid into human cells.An easily accessible sulfated saccharide mimetic inhibits in vitro human tumor cell adhesion and angiogenesis of vascular endothelial cells.Successful prediction of substrate-binding pocket in SLC17 transporter sialin.Systemic Fluorescence Imaging of Zebrafish Glycans with Bioorthogonal Chemistry.Regulation of integrin αV subunit expression by sulfatide in hepatocellular carcinoma cells.Metabolic glycoengineering: sialic acid and beyondMonitoring dynamic glycosylation in vivo using supersensitive click chemistryMetabolic oligosaccharide engineering: implications for selectin-mediated adhesion and leukocyte extravasation.Fluorescent mimetics of CMP-Neu5Ac are highly potent, cell-permeable polarization probes of eukaryotic and bacterial sialyltransferases and inhibit cellular sialylation.Azido sialic acids can modulate cell-surface interactions.Towards in vivo imaging of cancer sialylation.Metabolic Remodeling of Cell-Surface Sialic Acids: Principles, Applications, and Recent Advances.Harnessing cancer cell metabolism for theranostic applications using metabolic glycoengineering of sialic acid in breast cancer as a pioneering example.Fluorescent live-cell imaging of metabolically incorporated unnatural cyclopropene-mannosamine derivatives.Biochemical, Cellular, Physiological, and Pathological Consequences of Human Loss of N-Glycolylneuraminic Acid.Metabolic monosaccharides altered cell responses to anticancer drugs.Bioorthogonal metabolic glycoengineering of human larynx carcinoma (HEp-2) cells targeting sialic acid.Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking.Characterization of ligand binding to the bifunctional key enzyme in the sialic acid biosynthesis by NMR: II. Investigation of the ManNAc kinase functionality.A sialic acid-targeted near-infrared theranostic for signal activation based intraoperative tumor ablation.Modulation of cellular adhesion by glycoengineering.Extreme Activity of Drug Nanocrystals Coated with A Layer of Non-Covalent Polymers from Self-Assembled Boric Acid.Fluorination of mammalian cell surfaces via the sialic acid biosynthetic pathway.Expanding the diversity of unnatural cell-surface sialic acids.Photocrosslinking of glycoconjugates using metabolically incorporated diazirine-containing sugars.Improved cyclopropene reporters for probing protein glycosylation.Exploring the effect of sialic acid orientation on ligand-receptor interactions.Glycan-specific metabolic oligosaccharide engineering of C7-substituted sialic acids.
P2860
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P2860
Versatile biosynthetic engineering of sialic acid in living cells using synthetic sialic acid analogues.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Versatile biosynthetic enginee ...... nthetic sialic acid analogues.
@en
Versatile biosynthetic enginee ...... nthetic sialic acid analogues.
@nl
type
label
Versatile biosynthetic enginee ...... nthetic sialic acid analogues.
@en
Versatile biosynthetic enginee ...... nthetic sialic acid analogues.
@nl
prefLabel
Versatile biosynthetic enginee ...... nthetic sialic acid analogues.
@en
Versatile biosynthetic enginee ...... nthetic sialic acid analogues.
@nl
P2093
P2860
P356
P1476
Versatile biosynthetic enginee ...... nthetic sialic acid analogues.
@en
P2093
Cornelia Oetke
Lars R Mantey
Oliver T Keppler
Rainer Isecke
Reinhard Brossmer
Stephan Hinderlich
Werner Reutter
P2860
P304
P356
10.1074/JBC.M109973200
P407
P577
2001-12-20T00:00:00Z