Inhibition of protein kinase Cbeta prevents impaired endothelium-dependent vasodilation caused by hyperglycemia in humans.
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Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategiesRegenerative therapies for diabetic microangiopathyTwenty-five years since the discovery of endothelium-derived relaxing factor (EDRF): does a dysfunctional endothelium contribute to the development of type 2 diabetes?Acute hyperglycemia enhances oxidative stress and exacerbates myocardial infarction by activating nicotinamide adenine dinucleotide phosphate oxidase during reperfusion.Diabetic neuropathy: mechanisms to managementMolecular mechanisms of diabetic vascular complicationsProtein Kinases as Drug Development Targets for Heart Disease TherapyCurcumin supplementation could improve diabetes-induced endothelial dysfunction associated with decreased vascular superoxide production and PKC inhibitionActivation of protein kinase C isoforms and its impact on diabetic complications.Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications.Molecular insights and therapeutic targets for diabetic endothelial dysfunction.Inhibition of protein kinase Cbeta does not improve endothelial function in type 2 diabetesLink between free radicals and protein kinase C in glucose-induced alteration of vascular dilation.PKCbeta regulates ischemia/reperfusion injury in the lung.Coronary microvascular dysfunction in diabetes mellitus: A reviewSelective PKC beta inhibition with ruboxistaurin and endothelial function in type-2 diabetes mellitusTargeting Neovascularization in Ischemic Retinopathy: Recent AdvancesEpidermal growth factor receptor tyrosine kinase-mediated signalling contributes to diabetes-induced vascular dysfunction in the mesenteric bed.Protein kinase C inhibition ameliorates functional endothelial insulin resistance and vascular smooth muscle cell hypersensitivity to insulin in diabetic hypertensive ratsApurinic/apyrimidinic endonuclease 1 inhibits protein kinase C-mediated p66shc phosphorylation and vasoconstriction.Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease.Liraglutide improves hypertension and metabolic perturbation in a rat model of polycystic ovarian syndrome.Endothelial dysfunction as a predictor of cardiovascular disease in type 1 diabetes.Increased atherothrombotic burden in patients with diabetes mellitus and acute coronary syndrome: a review of antiplatelet therapyInhibition of insulin signaling in endothelial cells by protein kinase C-induced phosphorylation of p85 subunit of phosphatidylinositol 3-kinase (PI3K).Hyperglycemia and endothelial dysfunction in atherosclerosis: lessons from type 1 diabetes.Krüppel-like factor 2 suppression by high glucose as a possible mechanism of diabetic vasculopathyEffects of some anti-diabetic and cardioprotective agents on proliferation and apoptosis of human coronary artery endothelial cells.Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells.Vascular risk: diabetes.Reactive oxygen species signaling facilitates FOXO-3a/FBXO-dependent vascular BK channel β1 subunit degradation in diabetic mice.Decreased coronary microvascular reactivity after cardioplegic arrest in patients with uncontrolled diabetes mellitus.The pathogenesis of diabetic complications: the role of DNA injury and poly(ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity.Diabetes and cardiovascular disease: let's push forward with translational researchGender difference in rat aorta vasodilation after acute exposure to high glucose: involvement of protein kinase C beta and superoxide but not of Rho kinase.Changes in microvascular reactivity after cardiopulmonary bypass in patients with poorly controlled versus controlled diabetes.Diabetic peripheral neuropathy: should a chaperone accompany our therapeutic approach?The protein kinase C-beta inhibitor, ruboxistaurin, for the treatment of diabetic microvascular complications.The effect of direct renin inhibition alone and in combination with ACE inhibition on endothelial function, arterial stiffness, and renal function in type 1 diabetes.Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme.
P2860
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P2860
Inhibition of protein kinase Cbeta prevents impaired endothelium-dependent vasodilation caused by hyperglycemia in humans.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Inhibition of protein kinase C ...... ed by hyperglycemia in humans.
@en
Inhibition of protein kinase C ...... ed by hyperglycemia in humans.
@nl
type
label
Inhibition of protein kinase C ...... ed by hyperglycemia in humans.
@en
Inhibition of protein kinase C ...... ed by hyperglycemia in humans.
@nl
prefLabel
Inhibition of protein kinase C ...... ed by hyperglycemia in humans.
@en
Inhibition of protein kinase C ...... ed by hyperglycemia in humans.
@nl
P2093
P356
P1433
P1476
Inhibition of protein kinase C ...... ed by hyperglycemia in humans.
@en
P2093
Allison B Goldfine
Joshua A Beckman
Leslie A Garrett
Mark A Creager
Mary Beth Gordon
P304
P356
10.1161/HH0102.102359
P577
2002-01-01T00:00:00Z