Antibodies to GAD and tryptic fragments of islet 64K antigen as distinct markers for development of IDDM. Studies with identical twins.
about
Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetesIdentification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragmentApproaches in type 1 diabetes research: A status report.The 37/40-kilodalton autoantigen in insulin-dependent diabetes mellitus is the putative tyrosine phosphatase IA-2.Detection of pancreatic islet 64,000 M(r) autoantigens in insulin-dependent diabetes distinct from glutamate decarboxylaseAntigen-specific therapeutic approaches in Type 1 diabetesImportance of persistent cellular and humoral immune changes before diabetes develops: prospective study of identical twins.Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice.IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus.Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes.Autoimmunity and the pathogenesis of type 1 diabetes.Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512).Autoantigens in type 1 diabetes mellitus.Prediction and prevention of type I diabetes.Twin studies in auto-immune disease.Immunological studies on type 1 diabetes in identical twinsIntervention therapies for insulin-dependent diabetes.Characterization of distinct islet protein autoantigens associated with type 1 diabetes.Type I insulin-dependent diabetes mellitus: a model for autoimmune polygenic disorders.Current concepts and advances in clinical laboratory testing for autoimmune diseases.Identification of a dominant epitope of glutamic acid decarboxylase (GAD-65) recognized by autoantibodies in stiff-man syndromeExpression, characterization, processing and immunogenicity of an insulin-dependent diabetes mellitus autoantigen, IA-2, in Sf-9 cells.Advances in childhood onset diabetes.Enterovirus infection can induce immune responses that cross-react with beta-cell autoantigen tyrosine phosphatase IA-2/IAR.Combined analysis of islet cell antibodies which cross-react with mouse pancreas, antibodies to the M(r) 64,000 islet protein, and antibodies to glutamate decarboxylase in subjects at risk for IDDM.Antibodies to the protein tyrosine phosphatases IAR and IA-2 are associated with progression to insulin-dependent diabetes (IDDM) in first-degree relatives at-risk for IDDM.
P2860
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P2860
Antibodies to GAD and tryptic fragments of islet 64K antigen as distinct markers for development of IDDM. Studies with identical twins.
description
1992 nî lūn-bûn
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1992年の論文
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1992年学术文章
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1992年学术文章
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1992年学术文章
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1992年学术文章
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1992年学术文章
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1992年学术文章
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1992年學術文章
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name
Antibodies to GAD and tryptic ...... Studies with identical twins.
@en
Antibodies to GAD and tryptic ...... Studies with identical twins.
@nl
type
label
Antibodies to GAD and tryptic ...... Studies with identical twins.
@en
Antibodies to GAD and tryptic ...... Studies with identical twins.
@nl
prefLabel
Antibodies to GAD and tryptic ...... Studies with identical twins.
@en
Antibodies to GAD and tryptic ...... Studies with identical twins.
@nl
P2093
P356
P1433
P1476
Antibodies to GAD and tryptic ...... Studies with identical twins.
@en
P2093
Bottazzo GF
Christie MR
Hollands J
Shattock M
P304
P356
10.2337/DIAB.41.7.782
P407
P577
1992-07-01T00:00:00Z