Transcriptional activation of cytochrome P450 CYP2C45 by drugs is mediated by the chicken xenobiotic receptor (CXR) interacting with a phenobarbital response enhancer unit.
about
The evolution of drug-activated nuclear receptors: one ancestral gene diverged into two xenosensor genes in mammalsDrugs mediate the transcriptional activation of the 5-aminolevulinic acid synthase (ALAS1) gene via the chicken xenobiotic-sensing nuclear receptor (CXR).Cytochrome P450 CYP2 genes in the common cormorant: Evolutionary relationships with 130 diapsid CYP2 clan sequences and chemical effects on their expressionIncreased rodenticide exposure rate and risk of toxicosis in barn owls (Tyto alba) from southwestern Canada and linkage with demographic but not genetic factors.Functional characterization of a first avian cytochrome P450 of the CYP2D subfamily (CYP2D49)Avian cytochrome P450 (CYP) 1-3 family genes: isoforms, evolutionary relationships, and mRNA expression in chicken liver.Whole-Genome Identification, Phylogeny, and Evolution of the Cytochrome P450 Family 2 (CYP2) Subfamilies in BirdsInsight into the metabolic mechanism of scoparone on biomarkers for inhibiting Yanghuang syndromeTranscriptional regulation of chicken cytochrome P450 2D49 basal expression by CCAAT/enhancer-binding protein α and hepatocyte nuclear factor 4α.Nuclear receptors constitutive androstane receptor and pregnane X receptor activate a drug-responsive enhancer of the murine 5-aminolevulinic acid synthase gene.Hepatic and intestinal CYP3A expression and activity in broilers.LXR deficiency and cholesterol feeding affect the expression and phenobarbital-mediated induction of cytochromes P450 in mouse liver.Trichloroethylene perturbs HNF4a expression and activity in the developing chick heart.
P2860
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P2860
Transcriptional activation of cytochrome P450 CYP2C45 by drugs is mediated by the chicken xenobiotic receptor (CXR) interacting with a phenobarbital response enhancer unit.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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@zh-cn
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name
Transcriptional activation of ...... rbital response enhancer unit.
@en
Transcriptional activation of ...... he chicken xenobiotic receptor
@nl
type
label
Transcriptional activation of ...... rbital response enhancer unit.
@en
Transcriptional activation of ...... he chicken xenobiotic receptor
@nl
prefLabel
Transcriptional activation of ...... rbital response enhancer unit.
@en
Transcriptional activation of ...... he chicken xenobiotic receptor
@nl
P2093
P2860
P356
P1476
Transcriptional activation of ...... rbital response enhancer unit.
@en
P2093
Carmela Gnerre
John J Stegeman
Manuel Baader
Urs A Meyer
P2860
P304
15647-15653
P356
10.1074/JBC.M109882200
P407
P577
2002-02-26T00:00:00Z