Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes.
about
Cyclic AMP-dependent transcriptional up-regulation of phosphodiesterase 4D5 in human airway smooth muscle cells. Identification and characterization of a novel PDE4D5 promoterMutations in the area composita protein αT-catenin are associated with arrhythmogenic right ventricular cardiomyopathyRadixin assembles cAMP effectors Epac and PKA into a functional cAMP compartment: role in cAMP-dependent cell proliferationDirect binding of the beta1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activationSoluble adenylyl cyclase is localized to cilia and contributes to ciliary beat frequency regulation via production of cAMPAn anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamicsThe protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmiasLight modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium BeggiatoaMolecular details of cAMP generation in mammalian cells: a tale of two systemsAKAP18 contains a phosphoesterase domain that binds AMPRegulation of T-cell activation by phosphodiesterase 4B2 requires its dynamic redistribution during immunological synapse formationSelective coupling of type 6 adenylyl cyclase with type 2 IP3 receptors mediates direct sensitization of IP3 receptors by cAMPBioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoringCalcium-mediated, purinergic stimulation and polarized localization of calcium-sensitive adenylyl cyclase isoforms in human airway epitheliaDesign and development of genetically encoded fluorescent sensors to monitor intracellular chemical and physical parametersTargeting protein-protein interactions in complexes organized by A kinase anchoring proteinsCardiac cAMP: production, hydrolysis, modulation and detectionImaging alterations of cardiomyocyte cAMP microdomains in diseaseThe genetically encoded tool set for investigating cAMP: more than the sum of its partsStudying GPCR/cAMP pharmacology from the perspective of cellular structureRole of the bicarbonate-responsive soluble adenylyl cyclase in pH sensing and metabolic regulationPhosphodiesterases maintain signaling fidelity via compartmentalization of cyclic nucleotidesSpatial control of cAMP signalling in health and diseaseCompartmentalization of β-adrenergic signals in cardiomyocytesThe role of type 4 phosphodiesterases in generating microdomains of cAMP: large scale stochastic simulationsPersistent cAMP-signals triggered by internalized G-protein-coupled receptorsCalcium signals driven by single channel noiseInhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytesModulation of Compartmentalised Cyclic Nucleotide Signalling via Local Inhibition of Phosphodiesterase ActivityMissense mutations in desmocollin-2 N-terminus, associated with arrhythmogenic right ventricular cardiomyopathy, affect intracellular localization of desmocollin-2 in vitroDynamic regulation of cAMP synthesis through anchored PKA-adenylyl cyclase V/VI complexesRegulation of phosphodiesterase 3 and inducible cAMP early repressor in the heartFRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cellsA biphasic and brain-region selective down-regulation of cyclic adenosine monophosphate concentrations supports object recognition in the ratPhosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterasesLocalization of functional endothelin receptor signaling complexes in cardiac transverse tubulesOccurrence of A-kinase anchor protein and associated cAMP-dependent protein kinase in the inner compartment of mammalian mitochondriaIdentification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cellsDifferential association of phosphodiesterase 4D isoforms with beta2-adrenoceptor in cardiac myocytes
P2860
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P2860
Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Discrete microdomains with hig ...... rat neonatal cardiac myocytes.
@en
Discrete microdomains with hig ...... rat neonatal cardiac myocytes.
@nl
type
label
Discrete microdomains with hig ...... rat neonatal cardiac myocytes.
@en
Discrete microdomains with hig ...... rat neonatal cardiac myocytes.
@nl
prefLabel
Discrete microdomains with hig ...... rat neonatal cardiac myocytes.
@en
Discrete microdomains with hig ...... rat neonatal cardiac myocytes.
@nl
P356
P1433
P1476
Discrete microdomains with hig ...... rat neonatal cardiac myocytes.
@en
P2093
Tullio Pozzan
P304
P356
10.1126/SCIENCE.1069982
P407
P577
2002-03-01T00:00:00Z