Im7 folding mechanism: misfolding on a path to the native state.
about
Colicin biologyImplementation of a k/k0 Method to Identify Long-Range Structure in Transition States during Conformational Folding/Unfolding of ProteinsThe High-Resolution NMR Structure of the Early Folding Intermediate of the Thermus thermophilus Ribonuclease HAmino Acid Insertion Reveals a Necessary Three-Helical Intermediate in the Folding Pathway of the Colicin E7 Immunity Protein Im7Nonnative Interactions in the FF Domain Folding Pathway from an Atomic Resolution Structure of a Sparsely Populated Intermediate: An NMR Relaxation Dispersion StudyDe novo prediction of protein folding pathways and structure using the principle of sequential stabilizationPhi-value analysis of a three-state protein folding pathway by NMR relaxation dispersion spectroscopy.Folding kinetics of staphylococcal nuclease studied by tryptophan engineering and rapid mixing methods.Multiple folding pathways of the SH3 domain.Calculation of mutational free energy changes in transition states for protein folding.Protein folding and misfolding: mechanism and principles.Evolution, energy landscapes and the paradoxes of protein folding.Using hydroxyl radical footprinting to explore the free energy landscape of protein folding.Desolvation and development of specific hydrophobic core packing during Im7 folding.Perturbing the folding energy landscape of the bacterial immunity protein Im7 by site-specific N-linked glycosylation.Folding of a LysM domain: entropy-enthalpy compensation in the transition state of an ideal two-state folder.How well does a funneled energy landscape capture the folding mechanism of spectrin domains?Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein.Tuning the free-energy landscape of a WW domain by temperature, mutation, and truncation.Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins.Measurement of histidine pKa values and tautomer populations in invisible protein states.Demonstration of a low-energy on-pathway intermediate in a fast-folding protein by kinetics, protein engineering, and simulationNonnative interactions in coupled folding and binding processes of intrinsically disordered proteins.The N-terminal to C-terminal motif in protein folding and functionA comprehensive multidimensional-embedded, one-dimensional reaction coordinate for protein unfolding/folding.A protein folding pathway with multiple folding intermediates at atomic resolutionDynameomics: a comprehensive database of protein dynamics.A simple method for probing the mechanical unfolding pathway of proteins in detailDetermination of an ensemble of structures representing the intermediate state of the bacterial immunity protein Im7.Take home lessons from studies of related proteinsEvidence for close side-chain packing in an early protein folding intermediate previously assumed to be a molten globule.Frustration in biomoleculesHydrogen-exchange stability analysis of Bergerac-Src homology 3 variants allows the characterization of a folding intermediate in equilibriumOxidative folding intermediates with nonnative disulfide bridges between adjacent cysteine residues.Single-molecule fluorescence reveals sequence-specific misfolding in multidomain proteinsMicrosecond unfolding kinetics of sheep prion protein reveals an intermediate that correlates with susceptibility to classical scrapie.Dependence of internal friction on folding mechanism.Native contact density and nonnative hydrophobic effects in the folding of bacterial immunity proteins.The H2A-H2B dimeric kinetic intermediate is stabilized by widespread hydrophobic burial with few fully native interactions.Even with nonnative interactions, the updated folding transition states of the homologs Proteins G & L are extensive and similar
P2860
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P2860
Im7 folding mechanism: misfolding on a path to the native state.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Im7 folding mechanism: misfolding on a path to the native state.
@en
Im7 folding mechanism: misfolding on a path to the native state.
@en-gb
Im7 folding mechanism: misfolding on a path to the native state.
@nl
type
label
Im7 folding mechanism: misfolding on a path to the native state.
@en
Im7 folding mechanism: misfolding on a path to the native state.
@en-gb
Im7 folding mechanism: misfolding on a path to the native state.
@nl
prefLabel
Im7 folding mechanism: misfolding on a path to the native state.
@en
Im7 folding mechanism: misfolding on a path to the native state.
@en-gb
Im7 folding mechanism: misfolding on a path to the native state.
@nl
P356
P1476
Im7 folding mechanism: misfolding on a path to the native state.
@en
P2093
Andrew P Capaldi
Colin Kleanthous
P2888
P304
P356
10.1038/NSB757
P577
2002-03-01T00:00:00Z
P5875
P6179
1022937897