Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor.
about
Production of lentiviral vectorsRole of the mammalian target of rapamycin pathway in lentiviral vector transduction of hematopoietic stem cellsImmunization of mice with lentiviral vectors targeted to MHC class II+ cells is due to preferential transduction of dendritic cells in vivoEnhanced genetic modification of adult growth factor mobilized peripheral blood hematopoietic stem and progenitor cells with rapamycin.Induced pluripotent stem cells: Mechanisms, achievements and perspectives in farm animals.Characterization of resistance to rhabdovirus and retrovirus infection in a human myeloid cell line.CD133-targeted gene transfer into long-term repopulating hematopoietic stem cellsVesicular stomatitis virus enables gene transfer and transsynaptic tracing in a wide range of organismsChimeric antigen receptor-engineered T cells for the treatment of metastatic prostate cancer.Molecular Determinants of Vectofusin-1 and Its Derivatives for the Enhancement of Lentivirally Mediated Gene Transfer into Hematopoietic Stem/Progenitor Cells.Vpx mediated degradation of SAMHD1 has only a very limited effect on lentiviral transduction rate in ex vivo cultured HSPCs.Ruxolitinib and Polycation Combination Treatment Overcomes Multiple Mechanisms of Resistance of Pancreatic Cancer Cells to Oncolytic Vesicular Stomatitis Virus.Restriction of HIV-1-based lentiviral vectors in adult primary marrow-derived and peripheral mobilized human CD34+ hematopoietic stem and progenitor cells occurs prior to viral DNA integration.A Lentiviral Vector Allowing Physiologically Regulated Membrane-anchored and Secreted Antibody Expression Depending on B-cell Maturation Status.Retroviral Vectors for Cancer Gene Therapy.Leucine-rich repeat-containing G protein-coupled receptor 4 facilitates vesicular stomatitis virus infection by binding vesicular stomatitis virus glycoprotein.Selection of an optimal promoter for gene transfer in normal B cells.Detailed comparison of retroviral vectors and promoter configurations for stable and high transgene expression in human induced pluripotent stem cells.Virus-Mimetic Fusogenic Exosomes for Direct Delivery of Integral Membrane Proteins to Target Cell Membranes.Baboon envelope pseudotyped lentiviral vectors efficiently transduce human B cells and allow active factor IX B cell secretion in vivo in NOD/SCIDγc-/- mice.Viral Engineering of Chimeric Antigen Receptor Expression on Murine and Human T Lymphocytes.HIV-1 Vpr- and Reverse Transcription-Induced Apoptosis in Resting Peripheral Blood CD4 T Cells and Protection by Common Gamma-Chain Cytokines.Cyclosporin a and rapamycin relieve distinct lentiviral restriction blocks in hematopoietic stem and progenitor cells.CD105 is a surface marker for receptor-targeted gene transfer into human long-term repopulating hematopoietic stem cells.Deciphering the impact of parameters influencing transgene expression kinetics after repeated cell transduction with integration-deficient retroviral vectors.Envelope, please. And the award goes to…B Cell-Intrinsic Role for IRF5 in TLR9/BCR-Induced Human B Cell Activation, Proliferation, and Plasmablast Differentiation.Is Lgr4 essential for VSV- and VSV-G-pseudotyped lentiviral vector entry to cells?Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein.Clinical use of lentiviral vectors.Genetic Modification of T Cells.Industrializing Autologous Adoptive Immunotherapies: Manufacturing Advances and Challenges.Priming Human Repopulating Hematopoietic Stem and Progenitor Cells for Cas9/sgRNA Gene Targeting.Measles virus envelope pseudotyped lentiviral vectors transduce quiescent human HSCs at an efficiency without precedentSurface-Engineered Lentiviral Vectors for Selective Gene Transfer into Subtypes of LymphocytesThe IS2 Element Improves Transcription Efficiency of Integration-Deficient Lentiviral Vector EpisomesA Nontoxic Transduction Enhancer Enables Highly Efficient Lentiviral Transduction of Primary Murine T Cells and Hematopoietic Stem CellsImproved Lentiviral Gene Delivery to Mouse Liver by Hydrodynamic Vector Injection through Tail Veingeneration of human CD19-CAR T cells results in B-cell depletion and signs of cytokine release syndrome
P2860
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P2860
Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
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@zh-hant
name
Mystery solved: VSV-G-LVs do n ...... se they lack the LDL receptor.
@en
Mystery solved: VSV-G-LVs do n ...... se they lack the LDL receptor.
@nl
type
label
Mystery solved: VSV-G-LVs do n ...... se they lack the LDL receptor.
@en
Mystery solved: VSV-G-LVs do n ...... se they lack the LDL receptor.
@nl
prefLabel
Mystery solved: VSV-G-LVs do n ...... se they lack the LDL receptor.
@en
Mystery solved: VSV-G-LVs do n ...... se they lack the LDL receptor.
@nl
P2093
P50
P1433
P1476
Mystery solved: VSV-G-LVs do n ...... use they lack the LDL receptor
@en
P2093
Bruce E Torbett
Camille Lévy
Caroline Costa
Cathy X Wang
Fouzia Amirache
P304
P356
10.1182/BLOOD-2013-11-540641
P407
P577
2014-02-01T00:00:00Z