Mechanism of the reaction catalyzed by dihydrofolate reductase from Escherichia coli: pH and deuterium isotope effects with NADPH as the variable substrate.
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Crystal Structure of a Type II Dihydrofolate Reductase Catalytic Ternary Complex †Long-range structural effects in a second-site revertant of a mutant dihydrofolate reductaseA vibrational structure of 7,8-dihydrobiopterin bound to dihydroneopterin aldolase.Refolding of Escherichia coli dihydrofolate reductase: sequential formation of substrate binding sites.pH-dependent conformational changes in Escherichia coli dihydrofolate reductase revealed by Raman difference spectroscopyRole of water in the catalytic cycle of E. coli dihydrofolate reductase.Kinetic and chemical mechanism of the dihydrofolate reductase from Mycobacterium tuberculosisMultiple intermediates, diverse conformations, and cooperative conformational changes underlie the catalytic hydride transfer reaction of dihydrofolate reductase.Small temperature dependence of the kinetic isotope effect for the hydride transfer reaction catalyzed by Escherichia coli dihydrofolate reductase.Searching sequence space: two different approaches to dihydrofolate reductase catalysis.31P NMR and genetic analysis establish hinT as the only Escherchia coli purine nucleoside phosphoramidase and as essential for growth under high salt conditionsExpression, purification and characterization of recombinant mouse translation initiation factor eIF4E as a dihydrofolate reductase (DHFR) fusion protein.Catalytic and ligand binding properties of the FK506 binding protein FKBP12: effects of the single amino acid substitution of Tyr82 to LeuConformational change of the methionine 20 loop of Escherichia coli dihydrofolate reductase modulates pKa of the bound dihydrofolateTwo parallel pathways in the kinetic sequence of the dihydrofolate reductase from Mycobacterium tuberculosisVibrational structure of dihydrofolate bound to R67 dihydrofolate reductase.Inter-flavin electron transfer in cytochrome P450 reductase - effects of solvent and pH identify hidden complexity in mechanism.Evolutional design of a hyperactive cysteine- and methionine-free mutant of Escherichia coli dihydrofolate reductase.Molecular and enzymatic characterizations of novel bifunctional 3beta-hydroxysteroid dehydrogenases/C-4 decarboxylases from Arabidopsis thaliana.Stabilization of hyperactive dihydrofolate reductase by cyanocysteine-mediated backbone cyclization.
P2860
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P2860
Mechanism of the reaction catalyzed by dihydrofolate reductase from Escherichia coli: pH and deuterium isotope effects with NADPH as the variable substrate.
description
1988 nî lūn-bûn
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1988年の論文
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1988年学术文章
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1988年学术文章
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1988年学术文章
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1988年学术文章
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1988年学术文章
@zh-sg
1988年學術文章
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1988年學術文章
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1988年學術文章
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name
Mechanism of the reaction cata ...... DPH as the variable substrate.
@en
Mechanism of the reaction cata ...... DPH as the variable substrate.
@nl
type
label
Mechanism of the reaction cata ...... DPH as the variable substrate.
@en
Mechanism of the reaction cata ...... DPH as the variable substrate.
@nl
prefLabel
Mechanism of the reaction cata ...... DPH as the variable substrate.
@en
Mechanism of the reaction cata ...... DPH as the variable substrate.
@nl
P356
P1433
P1476
Mechanism of the reaction cata ...... DPH as the variable substrate.
@en
P2093
P304
P356
10.1021/BI00415A017
P407
P577
1988-07-01T00:00:00Z