Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses.
about
Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptorsExpression of the type 2 receptor for cysteinyl leukotrienes (CysLT2R) by human mast cells: Functional distinction from CysLT1RCysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association StudiesG-protein-coupled receptors and asthma endophenotypes: the cysteinyl leukotriene system in perspectiveCysteinyl leukotrienes: multi-functional mediators in allergic rhinitisCysteinyl leukotrienes and their receptors; emerging conceptsThe leukotriene E4 puzzle: finding the missing pieces and revealing the pathobiologic implicationsLeukotriene E4 elicits respiratory epithelial cell mucin release through the G-protein-coupled receptor, GPR99Cysteinyl leukotrienes and their receptors: bridging inflammation and colorectal cancerGPR17 regulates immune pulmonary inflammation induced by house dust mitesCysLT(1)R antagonists inhibit tumor growth in a xenograft model of colon cancerThe leukotriene receptor antagonist montelukast and its possible role in the cardiovascular field.Caveolin-1 alters the pattern of cytoplasmic Ca2+ oscillations and Ca2+-dependent gene expression by enhancing leukotriene receptor desensitizationCysteinyl-leukotriene type 1 receptors transduce a critical signal for the up-regulation of eosinophilopoiesis by interleukin-13 and eotaxin in murine bone marrowRole of group V phospholipase A2 in zymosan-induced eicosanoid generation and vascular permeability revealed by targeted gene disruption.Development of mast cells and importance of their tryptase and chymase serine proteases in inflammation and wound healing.Allergic conjunctivitis exacerbates corneal allograft rejection by activating Th1 and th2 alloimmune responses.Platelet-driven leukotriene C4-mediated airway inflammation in mice is aspirin-sensitive and depends on T prostanoid receptors.CysLT2 receptors interact with CysLT1 receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cells.Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienesCysteinyl leukotrienes impair hypoxic pulmonary vasoconstriction in endotoxemic mice.Group V secretory phospholipase A2 translocates to the phagosome after zymosan stimulation of mouse peritoneal macrophages and regulates phagocytosis.Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis.Impaired degranulation but enhanced cytokine production after Fc epsilonRI stimulation of diacylglycerol kinase zeta-deficient mast cells.Mast cell deficiency in Kit(W-sh) mice does not impair antibody-mediated arthritisCysteinyl leukotriene 2 receptor on dendritic cells negatively regulates ligand-dependent allergic pulmonary inflammation.Cysteinyl leukotrienes mediate the enhancing effects of indomethacin and aspirin on eosinophil production in murine bone marrow cultures.Immuno-enhancement effects of Lycium ruthenicum Murr. polysaccharide on cyclophosphamide-induced immunosuppression in mice.Mast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulation.Cysteinyl leukotriene 1 receptor controls the severity of chronic pulmonary inflammation and fibrosis.P2Y6 receptors require an intact cysteinyl leukotriene synthetic and signaling system to induce survival and activation of mast cells.GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4.Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s.Cys-leukotrienes promote fibrosis in a mouse model of eosinophil-mediated respiratory inflammation.Eicosanoids and their drugs in cardiovascular diseases: focus on atherosclerosis and stroke.Cytochrome P450 and Lipoxygenase Metabolites on Renal Function.Endogenous production of leukotriene D4 mediates autocrine survival and proliferation via CysLT1 receptor signalling in intestinal epithelial cells.High tumor mast cell density is associated with longer survival of colon cancer patients.Cysteinyl leukotriene 1 receptor influences intestinal polyp incidence in a gender-specific manner in the ApcMin/+ mouse model.Cysteinyl leukotriene-dependent [Ca2+]i responses to angiotensin II in cardiomyocytes.
P2860
Q24646354-7992CB7F-AEE2-4A28-B1BD-5785208BC2F4Q24673057-A28D3227-382B-4722-8950-B6B2FD20676DQ28067073-C3DE3728-9134-4F47-ACAF-4626BD760B4FQ28212087-8093DF27-7F87-4FDA-A021-FEDFC9176FCAQ28219122-013214F4-A54B-4624-9D5E-6F16C239668EQ28243252-CD25DE51-73CE-4CF9-AB9D-FCE9934F6AA1Q28253643-2575CF89-D15D-4E7C-8981-1CCD5C83C05AQ28275552-8E085268-4DE8-4555-9C6F-5F9026DFBADAQ28308101-C2C80E00-D83D-448C-B5D1-499DB962385AQ28512834-D0C7A855-BDC4-46F4-86AA-B626455084A3Q28536784-B3C71B15-1C4A-4FBD-A8E4-EC6CC3DC095DQ30234961-B4096795-1475-45E4-9391-5C089E5AF033Q33793032-328F970E-D4C3-4090-B45D-FC838712EB1AQ33806618-A829489D-18CC-4BDF-8313-6117B00A6FA2Q33947290-607BCAC5-77B1-4D08-8ED9-C903EDF55743Q33969412-4E9C6491-CD23-48CD-863C-CDE994F84DF1Q34023710-1ED6DFA6-26BE-4714-B771-ACEFEC6C3324Q34473270-CD5B43B0-E015-456F-BD92-20869C28C413Q34662206-B19260AB-6ADC-43EF-B4C1-694EBA595A57Q34681509-8461F0EE-804F-4882-9C0B-DBB8F5921BE6Q35357091-5876825C-4990-4D55-AABA-5EE465261F6CQ35677082-8A7C9CF7-6201-4493-8B52-6FF3616455ABQ35882459-3DB69545-A8DD-4657-AF5D-E87B2F12282FQ36228617-261443A2-1BBE-4F97-9E26-84C4C44CA138Q36229192-E01C4232-7D81-4455-8AB8-B68D954F7142Q36339008-A7495DCE-EDD8-4B17-A560-C0B246C70D2CQ36456881-3146C097-A5EC-4F87-B743-80F466644F99Q36492801-D1E1F99C-2C9F-44DF-8A69-F4E30B5640B5Q36819905-565B5F48-5C13-4779-9CFC-FDD391C9421FQ36853612-C871DFF2-D2AB-4BFE-AA4D-0237ADB61A02Q37041271-DB9460E9-3520-4D8F-B3C0-D8989562770BQ37261678-B9FD6146-A344-4052-B60A-8CD30B0292BFQ37549767-C4248EBC-80BC-46CC-94BB-92027398433DQ37596484-087BA423-A2EB-404B-9137-4FF638A670FAQ37995534-437AEC55-D992-4B95-BB3D-5F3229B0EC42Q38693289-DA8A3E4B-2196-4287-828D-41D45A151FD9Q40277131-56B61FAE-7D76-4A77-9537-518C8E8AAAD9Q40676318-6354D28A-C149-40FD-AB7F-4371C844E38AQ40852202-F5D1500D-47EC-458D-B3B8-065CA5C440A7Q44280848-9AC59CCA-4446-4166-A1FA-34EF48E0B686
P2860
Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Targeted gene disruption revea ...... acute inflammatory responses.
@en
Targeted gene disruption revea ...... acute inflammatory responses.
@nl
type
label
Targeted gene disruption revea ...... acute inflammatory responses.
@en
Targeted gene disruption revea ...... acute inflammatory responses.
@nl
prefLabel
Targeted gene disruption revea ...... acute inflammatory responses.
@en
Targeted gene disruption revea ...... acute inflammatory responses.
@nl
P2093
P2860
P356
P1476
Targeted gene disruption revea ...... acute inflammatory responses.
@en
P2093
Akiko Maekawa
K Frank Austen
Yoshihide Kanaoka
P2860
P304
20820-20824
P356
10.1074/JBC.M203163200
P407
P577
2002-04-03T00:00:00Z