Metabolic engineering of lactic acid bacteria, the combined approach: kinetic modelling, metabolic control and experimental analysis.
about
Efficient production of l-lactic acid by an engineered Thermoanaerobacterium aotearoense with broad substrate specificityTowards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesMetabolic engineering of lactic acid bacteria for the production of industrially important compoundsIdentification of a metabolic reaction network from time-series data of metabolite concentrationsStructural control of metabolic fluxk-OptForce: integrating kinetics with flux balance analysis for strain designMonte-Carlo modeling of the central carbon metabolism of Lactococcus lactis: insights into metabolic regulationQuantitative 2H NMR at natural abundance can distinguish the pathway used for glucose fermentation by lactic acid bacteria.Genome sequence and comparative genome analysis of Lactobacillus casei: insights into their niche-associated evolutionRole of phosphate in the central metabolism of two lactic acid bacteria--a comparative systems biology approach.Fine tuning of the lactate and diacetyl production through promoter engineering in Lactococcus lactis.Thematic review series: systems biology approaches to metabolic and cardiovascular disorders. Lipidomics: a global approach to lipid analysis in biological systems.The sensitivity and significance analysis of parameters in the model of pH regulation on lactic acid production by Lactobacillus bulgaricus.High-level production of the low-calorie sugar sorbitol by Lactobacillus plantarum through metabolic engineering.Tracing regulatory routes in metabolism using generalised supply-demand analysis.Metabolic models for rational improvement of lactic acid bacteria as cell factories.Overview on sugar metabolism and its control in Lactococcus lactis - the input from in vivo NMR.10 years of the nisin-controlled gene expression system (NICE) in Lactococcus lactis.Modelling strategies for the industrial exploitation of lactic acid bacteria.Modeling of enzyme production kinetics.PASMet: a web-based platform for prediction, modelling and analyses of metabolic systems.Metabolic control analysis: a tool for designing strategies to manipulate metabolic pathways.Understanding the industrial application potential of lactic acid bacteria through genomics.Approaches to biosimulation of cellular processes.Bridging the gap between fluxomics and industrial biotechnology.Mathematical models of cell factories: moving towards the core of industrial biotechnology.Systems biology of lactic acid bacteria: a critical review.A kinetic study of sugarcane sucrose synthase.Overproduction of heterologous mannitol 1-phosphatase: a key factor for engineering mannitol production by Lactococcus lactis.Metabolic engineering of mannitol production in Lactococcus lactis: influence of overexpression of mannitol 1-phosphate dehydrogenase in different genetic backgrounds.Toward quantitative understanding on microbial community structure and functioning: a modeling-centered approach using degradation of marine oil spills as example.Construction and validation of a detailed kinetic model of glycolysis in Plasmodium falciparum.Effect of different NADH oxidase levels on glucose metabolism by Lactococcus lactis: kinetics of intracellular metabolite pools determined by in vivo nuclear magnetic resonanceIS981-mediated adaptive evolution recovers lactate production by ldhB transcription activation in a lactate dehydrogenase-deficient strain of Lactococcus lactisThe pool of ADP and ATP regulates anaerobic product formation in resting cells of Lactococcus lactis.Bridging the gap between stochastic and deterministic regimes in the kinetic simulations of the biochemical reaction networks.Standardized assay medium to measure Lactococcus lactis enzyme activities while mimicking intracellular conditions.Reappraisal of the regulation of lactococcal L-lactate dehydrogenase.Decreased xylitol formation during xylose fermentation in Saccharomyces cerevisiae due to overexpression of water-forming NADH oxidase.13C based proteinogenic amino acid (PAA) and metabolic flux ratio analysis of Lactococcus lactis reveals changes in pentose phosphate (PP) pathway in response to agitation and temperature related stresses.
P2860
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P2860
Metabolic engineering of lactic acid bacteria, the combined approach: kinetic modelling, metabolic control and experimental analysis.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Metabolic engineering of lacti ...... rol and experimental analysis.
@en
Metabolic engineering of lacti ...... rol and experimental analysis.
@nl
type
label
Metabolic engineering of lacti ...... rol and experimental analysis.
@en
Metabolic engineering of lacti ...... rol and experimental analysis.
@nl
prefLabel
Metabolic engineering of lacti ...... rol and experimental analysis.
@en
Metabolic engineering of lacti ...... rol and experimental analysis.
@nl
P2093
P1433
P1476
Metabolic engineering of lacti ...... trol and experimental analysis
@en
P2093
Dirk E Martens
Iris I Van Swam
Jeroen Hugenholtz
Marcel H N Hoefnagel
Marjo J C Starrenburg
Michiel Kleerebezem
Roger Bongers
P304
P356
10.1099/00221287-148-4-1003
P577
2002-04-01T00:00:00Z