Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolism.
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Characterization of human cytochrome P450 enzymes catalyzing domperidone N-dealkylation and hydroxylation in vitroEfavirenz primary and secondary metabolism in vitro and in vivo: identification of novel metabolic pathways and cytochrome P450 2A6 as the principal catalyst of efavirenz 7-hydroxylationBaculovirus vectors: novel mammalian cell gene-delivery vehicles and their applications.Contributions of human cytochrome P450 enzymes to glyburide metabolism.Part 2: pharmacogenetic variability in drug transport and phase I anticancer drug metabolism.Metabolism and transport of oxazaphosphorines and the clinical implications.Gomisin A is a Novel Isoform-Specific Probe for the Selective Sensing of Human Cytochrome P450 3A4 in Liver Microsomes and Living Cells.Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevancePolymorphic CYP2B6: molecular mechanisms and emerging clinical significance.PhRMA white paper on ADME pharmacogenomics.Characterization of cytochrome P450s mediating ipriflavone metabolism in human liver microsomes.New potent and selective cytochrome P450 2B6 (CYP2B6) inhibitors based on three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis.High-throughput screening assays for CYP2B6 metabolism and inhibition using fluorogenic vivid substrates.In vitro metabolism and transport of the new dipeptidyl peptidase 4 inhibitors, KR66222 and KR66223.Identification and Characterization of CINPA1 Metabolites Facilitates Structure-Activity Studies of the Constitutive Androstane Receptor.CYP3A catalyses schizandrin biotransformation in human, minipig and rat liver microsomes.C-7 configuration as one of determinants in taxanes metabolism by human cytochrome P450 enzymes.Alteration of pharmacokinetics of cyclophosphamide and suppression of the cytochrome p450 genes by ciprofloxacin.CYP1A2 is the major isoform responsible for paeonol O-demethylation in human liver microsomes.Hydroxylation of tanshinone IIa in human liver microsomes is specifically catalysed by cytochrome P4502A6.Characterization of human cytochrome P450 isoforms involved in the metabolism of 7-epi-paclitaxel.In vitro metabolism of a new cardioprotective agent, KR-32570, in human liver microsomes.Molecular modelling of CYP2B6 based on homology with the CYP2C5 crystal structure: analysis of enzyme-substrate interactions.
P2860
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P2860
Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolism.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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@zh-sg
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name
Triethylenethiophosphoramide i ...... r cyclophosphamide metabolism.
@en
Triethylenethiophosphoramide i ...... r cyclophosphamide metabolism.
@nl
type
label
Triethylenethiophosphoramide i ...... r cyclophosphamide metabolism.
@en
Triethylenethiophosphoramide i ...... r cyclophosphamide metabolism.
@nl
prefLabel
Triethylenethiophosphoramide i ...... r cyclophosphamide metabolism.
@en
Triethylenethiophosphoramide i ...... r cyclophosphamide metabolism.
@nl
P356
P1476
Triethylenethiophosphoramide i ...... r cyclophosphamide metabolism.
@en
P2093
James M Rae
Nadia V Soukhova
P304
P356
10.1124/DMD.30.5.525
P577
2002-05-01T00:00:00Z