Selective presynaptic degeneration in the synaptopathy associated with ME7-induced hippocampal pathology.
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Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitroInsights into Mechanisms of Chronic NeurodegenerationNitric Oxide-Mediated Posttranslational Modifications: Impacts at the SynapseHow structure shapes (dys)function: a perspective to understanding brain region-specific degeneration in prion diseaseAmyloid oligomer neurotoxicity, calcium dysregulation, and lipid raftsEarly behavioral changes and quantitative analysis of neuropathological features in murine prion disease: stereological analysis in the albino Swiss mice model.A Drosophila model of GSS syndrome suggests defects in active zones are responsible for pathogenesis of GSS syndrome.Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation.Age and Environment Influences on Mouse Prion Disease Progression: Behavioral Changes and Morphometry and Stereology of Hippocampal Astrocytes.PrPSc accumulation in neuronal plasma membranes links Notch-1 activation to dendritic degeneration in prion diseases.HIV and SIV induce alterations in CNS CaMKII expression and activation: a potential mechanism for cognitive impairment.Morphological and functional abnormalities in mitochondria associated with synaptic degeneration in prion disease.The role of activity in synaptic degeneration in a protein misfolding disease, prion diseaseEarly Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficits in Three Distinct Strains of Prion Disease.Reduced expression of the presynaptic co-chaperone cysteine string protein alpha (CSPα) does not exacerbate experimentally-induced ME7 prion diseaseα-Synuclein stimulates a dopamine transporter-dependent chloride current and modulates the activity of the transporter.Striatal pathology underlies prion infection-mediated hyperactivity in mice.T-Tau and P-Tau in Brain and Blood from Natural and Experimental Prion Diseases.Antioxidant peroxiredoxin 6 protein rescues toxicity due to oxidative stress and cellular hypoxia in vitro, and attenuates prion-related pathology in vivoAt the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei.Plasma membrane invaginations containing clusters of full-length PrPSc are an early form of prion-associated neuropathology in vivo.Degenerating synaptic boutons in prion disease: microglia activation without synaptic strippingSynaptic dysfunction in prion diseases: a trafficking problem?Analysis of the hippocampal proteome in ME7 prion disease reveals a predominant astrocytic signature and highlights the brain-restricted production of clusterin in chronic neurodegeneration.The role of microglia in synaptic stripping and synaptic degeneration: a revised perspective.Allosteric function and dysfunction of the prion protein.Turning CALM into excitement: AP180 and CALM in endocytosis and disease.Alzheimer's disease Aβ assemblies mediating rapid disruption of synaptic plasticity and memory.An extracellular mechanism that can explain the neurotoxic effects of α-synuclein aggregates in the brainReview: membrane-associated misfolded protein propagation in natural transmissible spongiform encephalopathies (TSEs), synthetic prion diseases and Alzheimer's disease.Microglia and synapse: interactions in health and neurodegenerationMicrodissection and transcriptional profiling: a window into the pathobiology of preclinical prion disease.Comparison of abnormal isoform of prion protein in prion-infected cell lines and primary-cultured neurons by PrPSc-specific immunostaining.Silencing synapses: a route to understanding synapse degeneration in chronic neurodegenerative disease.The Role of Microglia in Prion Diseases: A Paradigm of Functional Diversity.Proteome Analysis of Potential Synaptic Vesicle Cycle Biomarkers in the Cerebrospinal Fluid of Patients with Sporadic Creutzfeldt-Jakob Disease.Proximity of SCG10 and prion protein in membrane rafts.Selective coexpression of synaptic proteins, α-synuclein, cysteine string protein-α, synaptophysin, synaptotagmin-1, and synaptobrevin-2 in vesicular acetylcholine transporter-immunoreactive axons in the guinea pig ileum.Human stem cell-derived astrocytes replicate human prions in a PRNP genotype-dependent manner.What Is Our Current Understanding of PrPSc-Associated Neurotoxicity and Its Molecular Underpinnings?
P2860
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P2860
Selective presynaptic degeneration in the synaptopathy associated with ME7-induced hippocampal pathology.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Selective presynaptic degenera ...... induced hippocampal pathology.
@en
Selective presynaptic degenera ...... induced hippocampal pathology.
@nl
type
label
Selective presynaptic degenera ...... induced hippocampal pathology.
@en
Selective presynaptic degenera ...... induced hippocampal pathology.
@nl
prefLabel
Selective presynaptic degenera ...... induced hippocampal pathology.
@en
Selective presynaptic degenera ...... induced hippocampal pathology.
@nl
P2093
P1476
Selective presynaptic degenera ...... induced hippocampal pathology.
@en
P2093
Bryony C Gray
V Hugh Perry
Vincent O'Connor
Zuzana Siskova
P356
10.1016/J.NBD.2009.04.001
P577
2009-04-10T00:00:00Z