Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis. - Wikidata - awgldk - TriplyDB

Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis.

Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis.

http://www.wikidata.org/entity/Q44028668

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Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway BOK and NOXA are essential mediators of p53-dependent apoptosis Caspases: pharmacological manipulation of cell death The enigma of caspase-2: the laymen's view The NRIF3 family of transcriptional coregulators induces rapid and profound apoptosis in breast cancer cells Caspase-2 activation in the absence of PIDDosome formation The PIDDosome, DNA-damage-induced apoptosis and beyond Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway Death Domain Assembly Mechanism Revealed by Crystal Structure of the Oligomeric PIDDosome Core Complex Cell death by mitotic catastrophe: a molecular definition New Arabidopsis thaliana cytochrome c partners: a look into the elusive role of cytochrome c in programmed cell death in plants Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.Inflammatory cells regulate p53 and caspases in acute pancreatitis Role of caspase 2 in apoptotic signaling in primate and murine germ cells Alternative programs of cell death in developing retinal tissue Multiple actions of pifithrin-alpha on doxorubicin-induced apoptosis in rat myoblastic H9c2 cells Caspase 2 activity contributes to the initial wave of germ cell apoptosis during the first round of spermatogenesis.Exposure to cell phone radiation up-regulates apoptosis genes in primary cultures of neurons and astrocytes.Characterization of cytoplasmic caspase-2 activation by induced proximity.Mechanisms of noise-induced hearing loss indicate multiple methods of prevention.Mitotic Catastrophe in BC3H1 Cells following Yessotoxin Exposure.Neonatal Hypoxia Ischaemia: Mechanisms, Models, and Therapeutic Challenges.Caspase-2-mediated cell death is required for deleting aneuploid cells.Overexpression of the anti-apoptotic caspase-2 short isoform in macrophage-derived foam cells of human atherosclerotic plaques Induction of apoptosis by enediyne antibiotic calicheamicin thetaII proceeds through a caspase-mediated mitochondrial amplification loop in an entirely Bax-dependent manner.Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kappaB.High LET radiation enhances apoptosis in mutated p53 cancer cells through Caspase-9 activation.Hepatitis C virus core protein and cellular protein HAX-1 promote 5-fluorouracil-mediated hepatocyte growth inhibition.Unilateral blood flow decrease induces bilateral and symmetric responses in the immature brain.Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis.NPRL2 sensitizes human non-small cell lung cancer (NSCLC) cells to cisplatin treatment by regulating key components in the DNA repair pathway.The late increase in intracellular free radical oxygen species during apoptosis is associated with cytochrome c release, caspase activation, and mitochondrial dysfunction.Processed caspase-2 can induce mitochondria-mediated apoptosis independently of its enzymatic activity.Berberine inhibits norepinephrine-induced apoptosis in neonatal rat cardiomyocytes via inhibiting ROS-TNF-α-caspase signaling pathway.Ocular neuroprotection by siRNA targeting caspase-2 DNA damage-induced apoptosis.Caspase 2 activation and ER stress drive rapid Jurkat cell apoptosis by clofibrate Mitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases.Loss of caspase-2-dependent apoptosis induces autophagy after mitochondrial oxidative stress in primary cultures of young adult cortical neurons.Metabolic control of Ca2+/calmodulin-dependent protein kinase II (CaMKII)-mediated caspase-2 suppression by the B55β/protein phosphatase 2A (PP2A)

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P2860

Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis.

http://www.wikidata.org/entity/Q44028668

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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2002年學術文章

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2002年學術文章

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name

Caspase-2 acts upstream of mit ...... g etoposide-induced apoptosis.

@en

Caspase-2 acts upstream of mit ...... g etoposide-induced apoptosis.

@nl

type

label

Caspase-2 acts upstream of mit ...... g etoposide-induced apoptosis.

@en

Caspase-2 acts upstream of mit ...... g etoposide-induced apoptosis.

@nl

prefLabel

Caspase-2 acts upstream of mit ...... g etoposide-induced apoptosis.

@en

Caspase-2 acts upstream of mit ...... g etoposide-induced apoptosis.

@nl

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Journal of Biological Chemistry

P1476

Caspase-2 acts upstream of mit ...... g etoposide-induced apoptosis.

@en

P2093

Boris Zhivotovsky

http://www.w3.org/2001/XMLSchema#string

John D Robertson

http://www.w3.org/2001/XMLSchema#string

Mari Enoksson

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Minna Suomela

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P2860

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2

Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis

Caspase-2-induced apoptosis is dependent on caspase-9, but its processing during UV- or tumor necrosis factor-dependent cell death requires caspase-3

Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

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29803-29809

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10.1074/JBC.M204185200

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33

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277

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