Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo.
about
Brain monoglyceride lipase participating in endocannabinoid inactivationA comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerolParsing the players: 2-arachidonoylglycerol synthesis and degradation in the CNSChemical probes of endocannabinoid metabolismAmygdala FAAH and anandamide: mediating protection and recovery from stressPreclinical Characterization of the FAAH Inhibitor JNJ-42165279Enzymatic pathways that regulate endocannabinoid signaling in the nervous systemEvidence for distinct roles in catalysis for residues of the serine-serine-lysine catalytic triad of fatty acid amide hydrolaseChronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system.Genetic manipulation of palmitoylethanolamide production and inactivation in Saccharomyces cerevisiae.In vivo pharmacology of endocannabinoids and their metabolic inhibitors: therapeutic implications in Parkinson's disease and abuse liabilityLocalization of the cannabinoid CB1 receptor and the 2-AG synthesizing (DAGLα) and degrading (MAGL, FAAH) enzymes in cells expressing the Ca(2+)-binding proteins calbindin, calretinin, and parvalbumin in the adult rat hippocampus.Regulation of inflammatory pain by inhibition of fatty acid amide hydrolase.Use of cannabinoids as a novel therapeutic modality against autoimmune hepatitis.The dual FAAH/MAGL inhibitor JZL195 has enhanced effects on endocannabinoid transmission and motor behavior in rats as compared to those of the MAGL inhibitor JZL184Endocannabinoid overloadCyclooxygenase-2 mediates anandamide metabolism in the mouse brainNo hypothermic response to serotonin in 5-HT7 receptor knockout mice.Functional disassociation of the central and peripheral fatty acid amide signaling systems.Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models.Cannabinoid type 1 receptor availability in the amygdala mediates threat processing in trauma survivors.A Cannabinoid CB1 Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive EffectsThe endocannabinoid system as a target for the treatment of visceral obesity and metabolic syndrome.Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells.Peroxisome proliferator-activated receptor α mediates acute effects of palmitoylethanolamide on sensory neuronsThe endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆(9)-tetrahydrocannabinol in fatty acid amide hydrolase knockout miceMembrane microdomains and metabolic pathways that define anandamide and 2-arachidonyl glycerol biosynthesis and breakdown.The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolaseInhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerolThe therapeutic potential of cannabis in multiple sclerosis.Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor.Manipulation of the endocannabinoid system by a general anaestheticCellular accumulation of anandamide: consensus and controversy.Oleamide: a member of the endocannabinoid family?The endocannabinoid system: a general view and latest additionsDifferential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation.Enhancement of the behavioral effects of endogenous and exogenous cannabinoid agonists by phenylmethyl sulfonyl fluoride.Interactions between endocannabinoids and stress-induced decreased sensitivity to natural reward.Cannabinoid withdrawal in mice: inverse agonist vs neutral antagonist.Critical enzymes involved in endocannabinoid metabolism
P2860
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P2860
Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Pharmacological activity of fa ...... acid amide hydrolase in vivo.
@en
Pharmacological activity of fa ...... acid amide hydrolase in vivo.
@nl
type
label
Pharmacological activity of fa ...... acid amide hydrolase in vivo.
@en
Pharmacological activity of fa ...... acid amide hydrolase in vivo.
@nl
prefLabel
Pharmacological activity of fa ...... acid amide hydrolase in vivo.
@en
Pharmacological activity of fa ...... acid amide hydrolase in vivo.
@nl
P2093
P356
P1476
Pharmacological activity of fa ...... acid amide hydrolase in vivo.
@en
P2093
Aron H Lichtman
E Gregory Hawkins
Graeme Griffin
P356
10.1124/JPET.302.1.73
P407
P577
2002-07-01T00:00:00Z