Insulin inhibits hepatocellular glucose production by utilizing liver-enriched transcriptional inhibitory protein to disrupt the association of CREB-binding protein and RNA polymerase II with the phosphoenolpyruvate carboxykinase gene promoter.
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Glycogen synthase kinase-3 regulates IGFBP-1 gene transcription through the thymine-rich insulin response elementPancreatic regulation of glucose homeostasisCells expressing the C/EBPbeta isoform, LIP, engulf their neighborsCCAAT/enhancer-binding protein family members recruit the coactivator CREB-binding protein and trigger its phosphorylationTranscriptional regulation of the glucose-6-phosphatase gene by cAMP/vasoactive intestinal peptide in the intestine. Role of HNF4alpha, CREM, HNF1alpha, and C/EBPalphaHepatocyte nuclear factor-4alpha contributes to carbohydrate-induced transcriptional activation of hepatic fatty acid synthasec-Myc is required for the glucose-mediated induction of metabolic enzyme genesThe synergistic effect of dexamethasone and all-trans-retinoic acid on hepatic phosphoenolpyruvate carboxykinase gene expression involves the coactivator p300FoxA2 involvement in suppression of protein C, an outcome predictor in experimental sepsisDephosphorylated C/EBPalpha accelerates cell proliferation through sequestering retinoblastoma protein.CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice.The C/EBPbeta isoform, liver-inhibitory protein (LIP), induces autophagy in breast cancer cell lines.Regulation of adipocyte 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) by CCAAT/enhancer-binding protein (C/EBP) β isoforms, LIP and LAP.Inhibition of glyceroneogenesis by histone deacetylase 3 contributes to lipodystrophy in mice with adipose tissue inflammation.CCAAT/enhancer-binding protein beta: its role in breast cancer and associations with receptor tyrosine kinases.Regulation of pyruvate dehydrogenase kinase 4 (PDK4) by CCAAT/enhancer-binding protein beta (C/EBPbeta)Insulin, CCAAT/enhancer-binding proteins and lactate regulate the human 11β-hydroxysteroid dehydrogenase type 2 gene expression in colon cancer cell lines.In pursuit of genes of glucose metabolismAn intronic locus control region plays an essential role in the establishment of an autonomous hepatic chromatin domain for the human vitamin D-binding protein gene.Glucocorticoid "programming" and PTSD risk.Transcriptional regulation by insulin: from the receptor to the gene.Deprivation of protein or amino acid induces C/EBPbeta synthesis and binding to amino acid response elements, but its action is not an absolute requirement for enhanced transcription.Regulation of elastin gene transcription by interleukin-1 beta-induced C/EBP beta isoforms.COP1 functions as a FoxO1 ubiquitin E3 ligase to regulate FoxO1-mediated gene expression.Pax-6 and c-Maf functionally interact with the alpha-cell-specific DNA element G1 in vivo to promote glucagon gene expression.CCAAT/enhancer-binding protein-beta participates in insulin-responsive expression of the factor VII gene.The beta-cell specific transcription factor Nkx6.1 inhibits glucagon gene transcription by interfering with Pax6.Protein kinase B activity is sufficient to mimic the effect of insulin on glucagon gene transcription.Peroxisomal proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1 alpha) enhances the thyroid hormone induction of carnitine palmitoyltransferase I (CPT-I alpha).Differential activation of a C/EBP beta isoform by a novel redox switch may confer the lipopolysaccharide-inducible expression of interleukin-6 gene.Splicing regulator SLU7 is essential for maintaining liver homeostasis.Stable conditional expression and effect of C/ebpβ-LIP in adipocytes using the pSLIK system.Severe impairment in liver insulin signaling fails to alter hepatic insulin action in conscious mice.Regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) gene expression by glucocorticoids and insulin.Elements of the glucocorticoid and retinoic acid response units are involved in cAMP-mediated expression of the PEPCK gene.Overexpression of beta2-adrenergic receptors in mouse liver alters the expression of gluconeogenic and glycolytic enzymes.Regulation of SREBP-1 expression and transcriptional action on HKII and FAS genes during fasting and refeeding in rat tissues.Regulation of elastin gene transcription by proteasome dysfunction.Glucocorticoids regulate transcription of the gene for phosphoenolpyruvate carboxykinase in the liver via an extended glucocorticoid regulatory unit.Prevention of HIF-1 activation and iNOS gene targeting by low-dose cadmium results in loss of myocardial hypoxic preconditioning in the rat.
P2860
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P2860
Insulin inhibits hepatocellular glucose production by utilizing liver-enriched transcriptional inhibitory protein to disrupt the association of CREB-binding protein and RNA polymerase II with the phosphoenolpyruvate carboxykinase gene promoter.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Insulin inhibits hepatocellula ...... e carboxykinase gene promoter.
@en
Insulin inhibits hepatocellula ...... e carboxykinase gene promoter.
@nl
type
label
Insulin inhibits hepatocellula ...... e carboxykinase gene promoter.
@en
Insulin inhibits hepatocellula ...... e carboxykinase gene promoter.
@nl
prefLabel
Insulin inhibits hepatocellula ...... e carboxykinase gene promoter.
@en
Insulin inhibits hepatocellula ...... e carboxykinase gene promoter.
@nl
P2093
P2860
P356
P1476
Insulin inhibits hepatocellula ...... e carboxykinase gene promoter.
@en
P2093
Daryl K Granner
David T Duong
Linda Sealy
Mary E Waltner-Law
Rosalie Sears
P2860
P304
32234-32242
P356
10.1074/JBC.M204873200
P407
P577
2002-06-17T00:00:00Z