Randomised, double-blind, placebo-controlled, dose-escalating phase I study of QGC001, a centrally acting aminopeptidase a inhibitor prodrug.
about
Combining a Clostridial enzyme exhibiting unusual active site plasticity with a remarkably facile sigmatropic rearrangement: rapid, stereocontrolled entry into densely functionalized fluorinated phosphonates for chemical biologyIdentification and characterization of novel inhibitors of Mammalian aspartyl aminopeptidaseNovel approaches for treating hypertensionAdvances in understanding the renin-angiotensin-aldosterone system (RAAS) in blood pressure control and recent pivotal trials of RAAS blockade in heart failure and diabetic nephropathy.Excess of Aminopeptidase A in the Brain Elevates Blood Pressure via the Angiotensin II Type 1 and Bradykinin B2 Receptors without Dipsogenic Effect.Future drug discovery in renin-angiotensin-aldosterone system intervention.Interventional procedures and future drug therapy for hypertension.Update on angiotensin II: new endocrine connections between the brain, adrenal glands and the cardiovascular system.Central and Peripheral Slow-Pressor Mechanisms Contributing to.Diurnal opposite variation between angiotensinase activities in photo-neuro-endocrine tissues of rats.
P2860
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P2860
Randomised, double-blind, placebo-controlled, dose-escalating phase I study of QGC001, a centrally acting aminopeptidase a inhibitor prodrug.
description
2014 nî lūn-bûn
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2014 թվականի ապրիլին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
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2014年学术文章
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2014年學術文章
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name
Randomised, double-blind, plac ...... peptidase a inhibitor prodrug.
@en
Randomised, double-blind, plac ...... peptidase a inhibitor prodrug.
@nl
type
label
Randomised, double-blind, plac ...... peptidase a inhibitor prodrug.
@en
Randomised, double-blind, plac ...... peptidase a inhibitor prodrug.
@nl
prefLabel
Randomised, double-blind, plac ...... peptidase a inhibitor prodrug.
@en
Randomised, double-blind, plac ...... peptidase a inhibitor prodrug.
@nl
P2093
P2860
P1476
Randomised, double-blind, plac ...... opeptidase a inhibitor prodrug
@en
P2093
Bernard P Roques
Damien Bergerot
Fabrice Balavoine
Michel Azizi
Nadia De Mota
Rémi Patouret
P2860
P2888
P304
P356
10.1007/S40262-013-0125-Y
P50
P577
2014-04-01T00:00:00Z