Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition.
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Paclitaxel targets VEGF-mediated angiogenesis in ovarian cancer treatmentAkt phosphorylation at Ser473 predicts benefit of paclitaxel chemotherapy in node-positive breast cancer.Akt mediates Ras downregulation of RhoB, a suppressor of transformation, invasion, and metastasisThe MEK1/2 inhibitor, selumetinib (AZD6244; ARRY-142886), enhances anti-tumour efficacy when combined with conventional chemotherapeutic agents in human tumour xenograft models.Effects for Sequential Treatment of siAkt and Paclitaxel on Gastric Cancer Cell Lines.Sulforaphane sensitizes human breast cancer cells to paclitaxel-induced apoptosis by downregulating the NF-κB signaling pathway.Downregulation of mitogen-activated protein kinase 1 of Leishmania donovani field isolates is associated with antimony resistance.Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells.[Expression and prognostic value of AKT2 in non-small cell lung cancer].
P2860
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P2860
Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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name
Inactivation of the antiapopto ...... tein kinase kinase inhibition.
@en
Inactivation of the antiapopto ...... tein kinase kinase inhibition.
@nl
type
label
Inactivation of the antiapopto ...... tein kinase kinase inhibition.
@en
Inactivation of the antiapopto ...... tein kinase kinase inhibition.
@nl
prefLabel
Inactivation of the antiapopto ...... tein kinase kinase inhibition.
@en
Inactivation of the antiapopto ...... tein kinase kinase inhibition.
@nl
P2093
P1476
Inactivation of the antiapopto ...... otein kinase kinase inhibition
@en
P2093
Deborah Hunter
Debra J Taxman
H Shelton Earp
Jeffrey P MacKeigan
Jenny P-Y Ting
Lee M Graves
P304
P407
P577
2002-07-01T00:00:00Z