A vacuolar-type H+-pyrophosphatase governs maintenance of functional acidocalcisomes and growth of the insect and mammalian forms of Trypanosoma brucei.
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Evolution of vacuolar proton pyrophosphatase domains and volutin granules: clues into the early evolutionary origin of the acidocalcisomeEvolution of energy metabolism and its compartmentation in KinetoplastidaRab32 is essential for maintaining functional acidocalcisomes, and for growth and infectivity of Trypanosoma cruzi.The structure and catalytic cycle of a sodium-pumping pyrophosphataseAcidocalcisomesNew insights into roles of acidocalcisomes and contractile vacuole complex in osmoregulation in protistsChannel-forming activities in the glycosomal fraction from the bloodstream form of Trypanosoma bruceiIdentification and characterization of an ecto-pyrophosphatase activity in intact epimastigotes of Trypanosoma rangeliCharacterization of a novel organelle in Toxoplasma gondii with similar composition and function to the plant vacuole.The SNARE protein family of Leishmania majorThe leishmania ARL-1 and Golgi traffic.The role of acidocalcisomes in parasitic protists.Evolution of acidocalcisomes and their role in polyphosphate storage and osmoregulation in eukaryotic microbesTbIRK is a signature sequence free potassium channel from Trypanosoma brucei locating to acidocalcisomes.Contribution of pyruvate phosphate dikinase in the maintenance of the glycosomal ATP/ADP balance in the Trypanosoma brucei procyclic form.Three-dimensional reconstruction of Trypanosoma cruzi epimastigotes and organelle distribution along the cell division cycle.Expansion of the target of rapamycin (TOR) kinase family and function in Leishmania shows that TOR3 is required for acidocalcisome biogenesis and animal infectivity.Target of rapamycin (TOR)-like 1 kinase is involved in the control of polyphosphate levels and acidocalcisome maintenance in Trypanosoma brucei.A vacuolar-H(+) -pyrophosphatase (TgVP1) is required for microneme secretion, host cell invasion, and extracellular survival of Toxoplasma gondiiA novel protein kinase localized to lipid droplets is required for droplet biogenesis in trypanosomes.Acidocalcisomes - conserved from bacteria to man.Proteomic analysis of the acidocalcisome, an organelle conserved from bacteria to human cells.Adaptor protein-3 (AP-3) complex mediates the biogenesis of acidocalcisomes and is essential for growth and virulence of Trypanosoma brucei.Ca2+ Regulation of Trypanosoma brucei Phosphoinositide Phospholipase C.Vacuolar ATPase depletion affects mitochondrial ATPase function, kinetoplast dependency, and drug sensitivity in trypanosomes.Acidocalcisome is required for autophagy in Trypanosoma brucei.A plethora of targets, a paucity of drugs: progress towards the development of novel chemotherapies for human African trypanosomiasis.Ostreococcus tauri is a new model green alga for studying iron metabolism in eukaryotic phytoplanktonProteomic analysis of acidocalcisomes of Trypanosoma brucei uncovers their role in phosphate metabolism, cation homeostasis, and calcium signalingPyrophosphate-fueled Na+ and H+ transport in prokaryotes.The acidocalcisome as a target for chemotherapeutic agents in protozoan parasites.Trypanosoma brucei vacuolar transporter chaperone 4 (TbVtc4) is an acidocalcisome polyphosphate kinase required for in vivo infection.Fate of glycosylphosphatidylinositol (GPI)-less procyclin and characterization of sialylated non-GPI-anchored surface coat molecules of procyclic-form Trypanosoma brucei.The acidocalcisome vacuolar transporter chaperone 4 catalyzes the synthesis of polyphosphate in insect-stages of Trypanosoma brucei and T. cruzi.Insights into the mechanism of membrane pyrophosphatases by combining experiment and computer simulation.The lysosomotropic drug LeuLeu-OMe induces lysosome disruption and autophagy-independent cell death in Trypanosoma brucei.Acidocalcisomes of eukaryotes.Ablation of a small transmembrane protein of Trypanosoma brucei (TbVTC1) involved in the synthesis of polyphosphate alters acidocalcisome biogenesis and function, and leads to a cytokinesis defect.Overexpression of a Zn2+-sensitive soluble exopolyphosphatase from Trypanosoma cruzi depletes polyphosphate and affects osmoregulation.CRISPR/Cas9-mediated endogenous C-terminal Tagging of Trypanosoma cruzi Genes Reveals the Acidocalcisome Localization of the Inositol 1,4,5-Trisphosphate Receptor.
P2860
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P2860
A vacuolar-type H+-pyrophosphatase governs maintenance of functional acidocalcisomes and growth of the insect and mammalian forms of Trypanosoma brucei.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
A vacuolar-type H+-pyrophospha ...... n forms of Trypanosoma brucei.
@en
A vacuolar-type H+-pyrophospha ...... n forms of Trypanosoma brucei.
@nl
type
label
A vacuolar-type H+-pyrophospha ...... n forms of Trypanosoma brucei.
@en
A vacuolar-type H+-pyrophospha ...... n forms of Trypanosoma brucei.
@nl
prefLabel
A vacuolar-type H+-pyrophospha ...... n forms of Trypanosoma brucei.
@en
A vacuolar-type H+-pyrophospha ...... n forms of Trypanosoma brucei.
@nl
P2093
P2860
P921
P356
P1476
A vacuolar-type H+-pyrophospha ...... n forms of Trypanosoma brucei.
@en
P2093
Claudia O Rodrigues
Guillaume Lemercier
Norbert Bakalara
Roberto Docampo
Sandrine Dutoya
Shuhong Luo
Théo Baltz
P2860
P304
37369-37376
P356
10.1074/JBC.M204744200
P407
P577
2002-07-16T00:00:00Z