Shedding of the transferrin receptor is mediated constitutively by an integral membrane metalloprotease sensitive to tumor necrosis factor alpha protease inhibitor-2.

Shedding of the transferrin receptor is mediated constitutively by an integral membrane metalloprotease sensitive to tumor necrosis factor alpha protease inhibitor-2.

Item
http://www.wikidata.org/entity/Q44090706
Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelinThe transferrin receptor-1 membrane stub undergoes intramembrane proteolysis by signal peptide peptidase-like 2bCatalytic properties of ADAM19Differential Inhibition of Signal Peptide Peptidase Family Members by Established γ-Secretase InhibitorsStroke-induced subventricular zone proliferation is promoted by tumor necrosis factor-alpha-converting enzyme protease activity.Biological and clinical aspects of soluble transferrin receptor.Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.Proteomic identification of desmoglein 2 and activated leukocyte cell adhesion molecule as substrates of ADAM17 and ADAM10 by difference gel electrophoresis.Molecular and cellular mechanisms of ectodomain sheddingARH directs megalin to the endocytic recycling compartment to regulate its proteolysis and gene expression.Release of the soluble transferrin receptor is directly regulated by binding of its ligand ferritransferrin.The murine goblet cell protein mCLCA3 is a zinc-dependent metalloprotease with autoproteolytic activity.Impaired autoproteolytic cleavage of mCLCA6, a murine integral membrane protein expressed in enterocytes, leads to cleavage at the plasma membrane instead of the endoplasmic reticulum.Mutational suppression of transferrin receptor shedding can be compensated by distinct metalloproteases acting on alternative sites.Implication of the proprotein convertases in iron homeostasis: proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin.Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood-brain barrier in vitro is dependent on its binding affinity
P2860

Shedding of the transferrin receptor is mediated constitutively by an integral membrane metalloprotease sensitive to tumor necrosis factor alpha protease inhibitor-2.

Item
http://www.wikidata.org/entity/Q44090706
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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name
Shedding of the transferrin re ...... or alpha protease inhibitor-2.
@en
Shedding of the transferrin re ...... or alpha protease inhibitor-2.
@nl
type
label
Shedding of the transferrin re ...... or alpha protease inhibitor-2.
@en
Shedding of the transferrin re ...... or alpha protease inhibitor-2.
@nl
prefLabel
Shedding of the transferrin re ...... or alpha protease inhibitor-2.
@en
Shedding of the transferrin re ...... or alpha protease inhibitor-2.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Shedding of the transferrin re ...... or alpha protease inhibitor-2.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698