Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer.
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Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasionLong-term effects of carbon containing engineered nanomaterials and asbestos in the lung: one year postexposure comparisonsMultiwalled carbon nanotube-induced gene signatures in the mouse lung: potential predictive value for human lung cancer risk and prognosisLive imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growthNitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activityCell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progressionDeletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancerIdentification of a myeloid-derived suppressor cell cystatin-like protein that inhibits metastasisMacrophage diversity enhances tumor progression and metastasisImaging and quantifying the dynamics of tumor-associated proteolysis.Computational analysis of the cathepsin B inhibitors activities through LR-MMPBSA binding affinity calculation based on docked complex.Successful expansion but not complete restriction of tropism of adeno-associated virus by in vivo biopanning of random virus display peptide librariesOverexpression of transcription factor Sp1 leads to gene expression perturbations and cell cycle inhibitionQSAR models for predicting cathepsin B inhibition by small molecules--continuous and binary QSAR models to classify cathepsin B inhibition activities of small molecules.Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients.IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion.Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.Induction of cathepsin B by the CXCR3 chemokines CXCL9 and CXCL10 in human breast cancer cellsMulti-conformation 3D QSAR study of benzenesulfonyl-pyrazol-ester compounds and their analogs as cathepsin B inhibitors.DNA accelerates the inhibition of human cathepsin V by serpins.Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.Pericellular proteolysis in cancerInterleukin-6 increases expression and secretion of cathepsin B by breast tumor-associated monocytesThe expression and activity of cathepsins D, H and K in asthmatic airways.Alternative activation of tumor-associated macrophages by IL-4: priming for protumoral functions.Tumor hypoxia enhances Non-Small Cell Lung Cancer metastasis by selectively promoting macrophage M2 polarization through the activation of ERK signaling.Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermisLessons in signaling and tumorigenesis from polyomavirus middle T antigen.Increased IL-10 mRNA expression in tumor-associated macrophage correlated with late stage of lung cancerSensing cytosolic RpsL by macrophages induces lysosomal cell death and termination of bacterial infectionA convenient route to diversely substituted icosahedral closomer nanoscaffolds.Gene expression analysis of macrophages that facilitate tumor invasion supports a role for Wnt-signaling in mediating their activity in primary mammary tumors.Live-cell imaging of tumor proteolysis: impact of cellular and non-cellular microenvironmentThe role of Cathepsin S as a marker of prognosis and predictor of chemotherapy benefit in adjuvant CRC: a pilot studyDifferential macrophage programming in the tumor microenvironment.Selective targeting of tumor and stromal cells by a nanocarrier system displaying lipidated cathepsin B inhibitor.Cigarette smoke condensate increases cathepsin-mediated invasiveness of oral carcinoma cellsMonocyte-derived macrophage assisted breast cancer cell invasion as a personalized, predictive metric to score metastatic risk.Differential Impact of Cysteine Cathepsins on Genetic Mouse Models of De novo Carcinogenesis: Cathepsin B as Emerging Therapeutic Target.Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells.
P2860
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P2860
Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Tumor cell-derived and macroph ...... metastasis of mammary cancer.
@en
Tumor cell-derived and macroph ...... metastasis of mammary cancer.
@nl
type
label
Tumor cell-derived and macroph ...... metastasis of mammary cancer.
@en
Tumor cell-derived and macroph ...... metastasis of mammary cancer.
@nl
prefLabel
Tumor cell-derived and macroph ...... metastasis of mammary cancer.
@en
Tumor cell-derived and macroph ...... metastasis of mammary cancer.
@nl
P2093
P50
P1433
P1476
Tumor cell-derived and macroph ...... g metastasis of mammary cancer
@en
P2093
Achim Krüger
Anna Papazoglou
Boye S Nielsen
Christoph Peters
Harald Brodoefel
Olga Vasiljeva
P304
P356
10.1158/0008-5472.CAN-05-4463
P407
P577
2006-05-01T00:00:00Z