Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity.
about
Cathepsin B is a New Drug Target for Traumatic Brain Injury Therapeutics: Evidence for E64d as a Promising Lead Drug CandidateCentral role of neutrophil in the pathogenesis of severe acute pancreatitisReview of experimental animal models of biliary acute pancreatitis and recent advances in basic researchNeurovascular and neuronal protection by E64d after focal cerebral ischemia in ratsProteomics portrait of archival lesions of chronic pancreatitisBeneficial effects of trypsin inhibitors derived from a spider venom peptide in L-arginine-induced severe acute pancreatitis in miceImmune-compromised state in the rat pancreas after chronic alcohol exposure: the role of peroxisome proliferator-activated receptor gammaActivation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells.Chinese Herbal Medicines Attenuate Acute Pancreatitis: Pharmacological Activities and Mechanisms.Catalpol ameliorates sodium taurocholate-induced acute pancreatitis in rats via inhibiting activation of nuclear factor kappa B.Risk factors for pancreatic cancer: underlying mechanisms and potential targets.Acute pancreatitis and organ failure: pathophysiology, natural history, and management strategies.A mouse model of acute biliary pancreatitis induced by retrograde pancreatic duct infusion of Na-taurocholate.Therapeutic proteasome inhibition in experimental acute pancreatitisActive cathepsins B, L, and S in murine and human pancreatitis.Recent insights into the cellular mechanisms of acute pancreatitis.Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection.Gardenia jasminoides protects against cerulein-induced acute pancreatitis.The role of heat shock proteins in gastrointestinal diseases.Specialized roles for cysteine cathepsins in health and disease.The role of protein synthesis and digestive enzymes in acinar cell injury.Exenatide does not evoke pancreatitis and attenuates chemically induced pancreatitis in normal and diabetic rodents."Heat shock protein 70 in pancreatic diseases: Friend or foe".Cathepsin B inhibition interferes with metastatic potential of human melanoma: an in vitro and in vivo studyRegulation of cathepsin B activity by 2A2 monoclonal antibody.The lysosome among targets of metformin: new anti-inflammatory uses for an old drug?Cathepsin B: Basis Sequence: Mouse.Protease-activated receptor-2 protects against pancreatitis by stimulating exocrine secretion.Legumain is activated in macrophages during pancreatitis.Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis.Release of Cathepsin B in Cytosol Causes Cell Death in Acute Pancreatitis.Proteasome inhibitor ameliorates severe acute pancreatitis and associated lung injury of rats.Trypsinogen activation in acute and chronic pancreatitis: is it a prerequisite?ADP-ribosylation factor 1 protein regulates trypsinogen activation via organellar trafficking of procathepsin B protein and autophagic maturation in acute pancreatitis.Pancreatic Inflammation Redirects Acinar to β Cell Reprogramming.Essential role of monocytes and macrophages in the progression of acute pancreatitis.Co-localization hypothesis: a mechanism for the intrapancreatic activation of digestive enzymes during the early phases of acute pancreatitis.Digesting new information about the role of trypsin in pancreatitis.Role of cathepsin B-mediated apoptosis in fulminant hepatic failure in mice.Protection against acute pancreatitis by activation of protease-activated receptor-2.
P2860
Q26782938-FEB7FA12-82CD-43F5-88C5-74A501089D37Q26801387-FF292AF4-303B-4F6C-BD0E-C508E92D0F2CQ27001120-32799986-E7FC-460A-9582-179EF70AB49CQ28248659-91D0FD90-1B33-482B-9336-853A238BA024Q28478126-AA14FD9B-D469-41BE-B1D6-6127AF7E2D2FQ28486191-D04E1C34-6C36-47C3-B2AA-729354594BFCQ28577532-BAE76585-5040-41DB-BCBB-36445557ABCBQ30479173-7745A19E-5DD4-46DC-9B26-9E5041804174Q33600107-448FF48B-7417-4550-8A9E-32D1826F4A3FQ34072319-198D6ABA-A8C5-4C15-B1A6-827E2421B587Q34400723-F4D3CEF4-7EBF-4F3C-9BDA-1813AD1F3AA8Q35801819-D1549D1A-1B9B-4AC7-B887-964B542D624CQ36172703-6612690A-9D11-4CF8-BCFE-DB0E8E780B6FQ36179048-5B6503A6-025D-4E19-A3E4-B4C62A4A88BEQ36312705-532EA902-2502-4F7E-BF74-30211C22B38DQ36709198-1C675DA5-6C93-421E-BF74-068602798A82Q37272093-895E81F3-EB53-4A0E-BFD6-EFDDB96AC4C9Q37386592-00D6BB99-A974-4A9A-A4AA-B4A808AA6B0BQ37516972-A60DA674-658F-4BAB-A12D-765238F40692Q37797839-EE2A22A9-85E3-46E9-9992-CBD0B88D9038Q38090903-D888513B-C2B8-4CD1-AF4F-98013F617EC9Q38340339-BA157D82-0EEB-4F00-896B-B3BB8602272BQ39329712-9EEFC889-424A-443A-833F-FB2DAC2C0538Q39671546-2A0C9075-B9E7-4DEF-8BF0-A2BE2CD84781Q39816609-5376181B-641D-4E4B-9DFC-DA616CF67580Q39882878-A2E27981-5221-4F6B-9407-AE6E7AD2F74CQ41230243-24A85779-A3B2-430C-BB6A-7DFE2EFDA9CCQ41394674-735363E4-7A51-4A22-8826-5CFB854CF2AFQ41546015-625F0730-260F-47EA-9F77-F93F5469C562Q41628354-FCA5590E-EC9D-4097-8DAD-B5453FDC2DADQ41642231-AB6129BA-7C0F-4B4D-BE3C-898109D4915AQ41913060-8D44E979-7CE7-4754-8F20-A8063FBDF284Q42155388-6780E422-32F6-4164-A8F0-A4E4DB7569C4Q42238474-282AD437-9D62-4C99-9072-D78EE912B179Q42360719-839D202A-258C-4C76-8BC7-FF2E82C265D4Q42478797-C745C4AC-657A-4C32-9600-B8480951700EQ42726070-9EC5AA5B-431A-45F1-AE1A-D6B08D096315Q43146280-17439676-7BF9-428E-B8AE-40072CFF8034Q43159008-A214A7DB-9629-48F8-AA91-855A951FA474Q45086307-75A97D97-7EED-4AF7-90BD-2927C428BADF
P2860
Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity.
@en
Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity.
@nl
type
label
Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity.
@en
Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity.
@nl
prefLabel
Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity.
@en
Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity.
@nl
P2093
P356
P1476
Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity.
@en
P2093
Albert M Song
Ashok K Saluja
Gijs J D Van Acker
Lakshmi Bhagat
Michael L Steer
Vijay P Singh
P304
P356
10.1152/AJPGI.00363.2001
P577
2002-09-01T00:00:00Z