Methapyrilene toxicity: anchorage of pathologic observations to gene expression alterations.
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New perspectives for in vitro risk assessment of multiwalled carbon nanotubes: application of coculture and bioinformaticsMultiwalled carbon nanotube-induced gene signatures in the mouse lung: potential predictive value for human lung cancer risk and prognosisBlood transcriptomics: applications in toxicologyMolecular insights into the progression of crystalline silica-induced pulmonary toxicity in ratsMechanisms of crystalline silica-induced pulmonary toxicity revealed by global gene expression profilingCombined histomorphometric and gene-expression profiling applied to toxicologyOverview of an interlaboratory collaboration on evaluating the effects of model hepatotoxicants on hepatic gene expression.Interlaboratory evaluation of rat hepatic gene expression changes induced by methapyrilene.Quantitative PCR deconstruction of discrepancies between results reported by different hybridization platforms.Overview on the application of transcription profiling using selected nephrotoxicants for toxicology assessment.Identification of putative gene based markers of renal toxicityDiscriminating different classes of toxicants by transcript profilingMolecular characterization of thyroid toxicity: anchoring gene expression profiles to biochemical and pathologic end points.Toxicogenomic applications to drug risk assessment.Gene expression analysis of the hepatotoxicant methapyrilene in primary rat hepatocytes: an interlaboratory study.Effect of chemical mutagens and carcinogens on gene expression profiles in human TK6 cellsSimultaneous clustering of gene expression data with clinical chemistry and pathological evaluations reveals phenotypic prototypes.Application of toxicogenomics to toxicology: basic concepts in the analysis of microarray data.New insights into functional aspects of liver morphology.Systematic variation normalization in microarray data to get gene expression comparison unbiased.Application of visualization tools to the analysis of histopathological data enhances biological insight and interpretation.Heat map visualization of high-density clinical chemistry data.Clustering of gene expression data and end-point measurements by simulated annealing.Use of transcriptomics in understanding mechanisms of drug-induced toxicityThe evolution of bioinformatics in toxicology: advancing toxicogenomicsIdentification of genes implicated in methapyrilene-induced hepatotoxicity by comparing differential gene expression in target and nontarget tissue.Toxicogenomics: regulatory perspective on current position.Blood gene expression signatures predict exposure levels.Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype.A metabolomics investigation of non-genotoxic carcinogenicity in the rat.Contribution of new technologies to characterization and prediction of adverse effects.Literature-based compound profiling: application to toxicogenomics.The role of drug profiles as similarity metrics: applications to repurposing, adverse effects detection and drug-drug interactions.Validation of Transcriptomics-Based In Vitro Methods.A gene expression signature that predicts the future onset of drug-induced renal tubular toxicity.Connexin-based signaling and drug-induced hepatotoxicity.Diagnosis of drug-induced renal tubular toxicity using global gene expression profiles.Cytokines associated with increased erythropoiesis in Sprague-Dawley rats administered a novel hyperglycosylated analog of recombinant human erythropoietin.Gene expression profiling of rat livers reveals indicators of potential adverse effects.Differential gene expression profiling in whole blood during acute systemic inflammation in lipopolysaccharide-treated rats.
P2860
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P2860
Methapyrilene toxicity: anchorage of pathologic observations to gene expression alterations.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Methapyrilene toxicity: anchor ...... o gene expression alterations.
@en
Methapyrilene toxicity: anchor ...... o gene expression alterations.
@nl
type
label
Methapyrilene toxicity: anchor ...... o gene expression alterations.
@en
Methapyrilene toxicity: anchor ...... o gene expression alterations.
@nl
prefLabel
Methapyrilene toxicity: anchor ...... o gene expression alterations.
@en
Methapyrilene toxicity: anchor ...... o gene expression alterations.
@nl
P2093
P2860
P1476
Methapyrilene toxicity: anchor ...... to gene expression alterations
@en
P2093
Astrid C Haugen
Brian L Knight
Cynthia A Afshari
Hisham K Hamadeh
Kerry Blanchard
Michael L Cunningham
Pierre R Bushel
Raymond Stoll
Raymond W Tennant
Rupesh P Amin
P2860
P304
P356
10.1080/01926230290105712
P407
P577
2002-07-01T00:00:00Z