Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6
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Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferationEvidence of p53-dependent cross-talk between ribosome biogenesis and the cell cycle: effects of nucleolar protein Bop1 on G(1)/S transitionA CPSF-73 homologue is required for cell cycle progression but not cell growth and interacts with a protein having features of CPSF-100Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complexEssential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activationThe human ribosomal protein genes: sequencing and comparative analysis of 73 geneshDREF regulates cell proliferation and expression of ribosomal protein genesMany ribosomal protein genes are cancer genes in zebrafishTargeted cancer therapy with ribosome biogenesis inhibitors: a real possibility?Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instabilityGuarding the 'translation apparatus': defective ribosome biogenesis and the p53 signaling pathwayGenes encoding ribosomal proteins Rps0A/B of Saccharomyces cerevisiae interact with TOM1 mutants defective in ribosome synthesisA nucleolar protein related to ribosomal protein L7 is required for an early step in large ribosomal subunit biogenesis.A survey of essential gene function in the yeast cell division cycleA dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size.Role of ribosomal protein mutations in tumor development (Review)Attenuation of 40S ribosomal subunit abundance differentially affects host and HCV translation and suppresses HCV replicationRibosomal protein S6 gene haploinsufficiency is associated with activation of a p53-dependent checkpoint during gastrulationInactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response.Ribosomal protein S6 phosphorylation and function during late gestation liver development in the ratRibosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis.Ribosomal protein L24 defect in belly spot and tail (Bst), a mouse MinutePescadillo is essential for nucleolar assembly, ribosome biogenesis, and mammalian cell proliferationA protein inventory of human ribosome biogenesis reveals an essential function of exportin 5 in 60S subunit exportEffects of partial suppression of ribosomal protein S6 on organ formation in Arabidopsis thaliana.The ribosomal protein Rpl22 controls ribosome composition by directly repressing expression of its own paralog, Rpl22l1Nuclear ribosome biogenesis mediated by the DIM1A rRNA dimethylase is required for organized root growth and epidermal patterning in Arabidopsis.Targeting the translational machinery as a novel treatment strategy for hematologic malignanciesRibosomopathies: human disorders of ribosome dysfunction.Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition.Regulation of blood-testis barrier (BTB) dynamics during spermatogenesis via the "Yin" and "Yang" effects of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2.O-GlcNAc cycling enzymes associate with the translational machinery and modify core ribosomal proteinsTumor induction by an Lck-MyrAkt transgene is delayed by mechanisms controlling the size of the thymus.mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver.Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesisWhen ribosomes go bad: diseases of ribosome biogenesis.Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylationUbiquitin and ubiquitin-like proteins in the nucleolus: multitasking tools for a ribosome factory.The emerging importance of ribosomal dysfunction in the pathogenesis of hematologic disorders.
P2860
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P2860
Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6
description
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2000
@ast
im Juni 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/06/16)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/06/16)
@nl
наукова стаття, опублікована в червні 2000
@uk
name
Proliferation, but not growth, ...... on of 40S ribosomal protein S6
@ast
Proliferation, but not growth, ...... on of 40S ribosomal protein S6
@en
Proliferation, but not growth, ...... on of 40S ribosomal protein S6
@nl
type
label
Proliferation, but not growth, ...... on of 40S ribosomal protein S6
@ast
Proliferation, but not growth, ...... on of 40S ribosomal protein S6
@en
Proliferation, but not growth, ...... on of 40S ribosomal protein S6
@nl
prefLabel
Proliferation, but not growth, ...... on of 40S ribosomal protein S6
@ast
Proliferation, but not growth, ...... on of 40S ribosomal protein S6
@en
Proliferation, but not growth, ...... on of 40S ribosomal protein S6
@nl
P2093
P50
P3181
P1433
P1476
Proliferation, but not growth, ...... on of 40S ribosomal protein S6
@en
P2093
B Ledermann
F Zilberman
L Terracciano
M J Stewart
P304
P3181
P356
10.1126/SCIENCE.288.5473.2045
P407
P577
2000-06-01T00:00:00Z