RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation.
about
The RAG1 N-terminal domain is an E3 ubiquitin ligaseVprBP binds full-length RAG1 and is required for B-cell development and V(D)J recombination fidelityMMP13 mutation causes spondyloepimetaphyseal dysplasia, Missouri type (SEMD(MO)SUMO modification of human XRCC4 regulates its localization and function in DNA double-strand break repair.Putting the pieces together: identification and characterization of structural domains in the V(D)J recombination protein RAG1Recombination-activating gene proteins: more regulation, pleaseBood POZ containing gene type 2 is a human counterpart of yeast Btb3p and promotes the degradation of terminal deoxynucleotidyltransferaseAutoubiquitylation of the V(D)J recombinase protein RAG1Spatio-temporal regulation of RAG2 following genotoxic stress.The bounty of RAGs: recombination signal complexes and reaction outcomes.Role of RAG1 autoubiquitination in V(D)J recombination.Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phaseImpaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice.Karyopherin alpha 1 is a putative substrate of the RAG1 ubiquitin ligase.Ubiquitination events that regulate recombination of immunoglobulin Loci gene segments.Riches in RAGs: Revealing the V(D)J Recombinase through High-Resolution Structures.Alternative pathways for the repair of RAG-induced DNA breaksHuman pre-B cell receptor signal transduction: evidence for distinct roles of PI3kinase and MAP-kinase signalling pathways.Interleukin-6 is responsible for aberrant B-cell receptor-mediated regulation of RAG expression in systemic lupus erythematosus.
P2860
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P2860
RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation.
@en
RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation.
@nl
type
label
RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation.
@en
RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation.
@nl
prefLabel
RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation.
@en
RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation.
@nl
P2093
P2860
P356
P1476
RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation.
@en
P2093
Daisuke Kitamura
Midori Mizuta
Ryushin Mizuta
Shinsuke Araki
P2860
P304
41423-41427
P356
10.1074/JBC.M206605200
P407
P577
2002-08-29T00:00:00Z