Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B. - Wikidata - awgldk - TriplyDB

Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B.

Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B.

http://www.wikidata.org/entity/Q44126933

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Synergistic antileukemic interactions between 2-medroxyestradiol (2-ME) and histone deacetylase inhibitors involve Akt down-regulation and oxidative stress Purinergic receptor-mediated rapid depletion of nuclear phosphorylated Akt depends on pleckstrin homology domain leucine-rich repeat phosphatase, calcineurin, protein phosphatase 2A, and PTEN phosphatases Defect of insulin signal in peripheral tissues: Important role of ceramide Ceramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ Accumulation Molecular requirements for doxorubicin-mediated death in murine oocytes Anthraquinone G503 induces apoptosis in gastric cancer cells through the mitochondrial pathway p75NTR-dependent modulation of cellular handling of reactive oxygen species Protein kinase Akt/PKB phosphorylates heme oxygenase-1 in vitro and in vivo.Neonatal exendin-4 treatment reduces oxidative stress and prevents hepatic insulin resistance in intrauterine growth-retarded rats.High fluence low-power laser irradiation induces apoptosis via inactivation of Akt/GSK3β signaling pathway.The scavenging of superoxide radicals promotes apoptosis induced by a novel cell-permeable fusion protein, sTRAIL:FeSOD, in tumor necrosis factor-related apoptosis-inducing ligand-resistant leukemia cells.Protein phosphatase magnesium dependent 1A (PPM1A) plays a role in the differentiation and survival processes of nerve cells.Tp53-induced glycolysis and apoptosis regulator (TIGAR) protects glioma cells from starvation-induced cell death by up-regulating respiration and improving cellular redox homeostasis Inhibition of PI3K/AKT/mTOR axis disrupts oxidative stress-mediated survival of melanoma cells.Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy Isoform-specific regulation of Akt by PDGF-induced reactive oxygen species.Protective effect of butylated hydroxylanisole against hydrogen peroxide-induced apoptosis in primary cultured mouse hepatocytes.Differential modulation of Akt/glycogen synthase kinase-3beta pathway regulates apoptotic and cytoprotective signaling responses Defective Expression of the Mitochondrial-tRNA Modifying Enzyme GTPBP3 Triggers AMPK-Mediated Adaptive Responses Involving Complex I Assembly Factors, Uncoupling Protein 2, and the Mitochondrial Pyruvate Carrier.Requirement of dendritic Akt degradation by the ubiquitin-proteasome system for neuronal polarity.Cadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epidermal cells.Decreased ceramide transport protein (CERT) function alters sphingomyelin production following UVB irradiation.TRAIL-induced apoptosis in gliomas is enhanced by Akt-inhibition and is independent of JNK activation Stimulation of Akt poly-ubiquitination and proteasomal degradation in P388D1 cells by 7-ketocholesterol and 25-hydroxycholesterol.The Antiapoptosis Effect of Glycyrrhizate on HepG2 Cells Induced by Hydrogen Peroxide.Acyl-CoA synthetase VL3 knockdown inhibits human glioma cell proliferation and tumorigenicity.p53 and regulation of bioactive sphingolipids.Tris(2-chloroethyl)phosphate-induced cell growth arrest via attenuation of SIRT1-independent PI3K/Akt/mTOR pathway.13-Oxyingenol dodecanoate, a cytotoxic ingenol derivative, induces mitochondrial apoptosis and caspase-dependent Akt decrease in K562 cells.Chelation of lysosomal iron protects dopaminergic SH-SY5Y neuroblastoma cells from hydrogen peroxide toxicity by precluding autophagy and Akt dephosphorylation.Survive or thrive: tradeoff strategy for cellular senescence.Resolvin E1 maintains macrophage function under cigarette smoke-induced oxidative stress.SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.Signaling and apoptosis differences between severe hypoxia and desferoxamine treatment of human epithelial cells.Tumor necrosis factor-alpha-stimulated cell proliferation is mediated through sphingosine kinase-dependent Akt activation and cyclin D expression.Molecular cloning and functional characterization of a cell-permeable superoxide dismutase targeted to lung adenocarcinoma cells. Inhibition cell proliferation through the Akt/p27kip1 pathway.Extracellular signal-regulated kinase activation delays hyperoxia-induced epithelial cell death in conditions of Akt downregulation.Ceramide sensitizes astrocytes to oxidative stress: protective role of cannabinoids.AKT/protein kinase B regulation of BCL family members during oxysterol-induced apoptosis.Febuxostat improves outcome in a rat model of cancer cachexia.

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P2860

Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B.

http://www.wikidata.org/entity/Q44126933

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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2002年學術文章

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2002年學術文章

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name

Ceramide and reactive oxygen s ...... ation of Akt/protein kinase B.

@en

Ceramide and reactive oxygen s ...... ation of Akt/protein kinase B.

@nl

type

label

Ceramide and reactive oxygen s ...... ation of Akt/protein kinase B.

@en

Ceramide and reactive oxygen s ...... ation of Akt/protein kinase B.

@nl

prefLabel

Ceramide and reactive oxygen s ...... ation of Akt/protein kinase B.

@en

Ceramide and reactive oxygen s ...... ation of Akt/protein kinase B.

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Ceramide and reactive oxygen s ...... ation of Akt/protein kinase B.

@en

P2093

Daniel Martin

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Marta Salinas

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Naoya Fujita

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Takashi Tsuruo

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P2860

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

Neurotrophins: roles in neuronal development and function

Ceramide generation by two distinct pathways in tumor necrosis factor alpha-induced cell death

Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis

Enhanced phosphorylation of p53 by ATM in response to DNA damage

The comet assay: what can it really tell us?

BCL-2 family members and the mitochondria in apoptosis

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

Cancer. p53, guardian of the genome

A neutral magnesium-dependent sphingomyelinase isoform associated with intracellular membranes and reversibly inhibited by reactive oxygen species.

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42943-42952

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scholarly article

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10.1074/JBC.M201070200

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45

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277

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Antonio Cuadrado

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2002-09-03T00:00:00Z

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12213802

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