Enhanced phosphorylation of p53 by ATM in response to DNA damage - Wikidata - awgldk - TriplyDB

Enhanced phosphorylation of p53 by ATM in response to DNA damage

Enhanced phosphorylation of p53 by ATM in response to DNA damage

http://www.wikidata.org/entity/Q28609838

about

Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapy Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activity Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex A role for ATR in the DNA damage-induced phosphorylation of p53 ATM-dependent phosphorylation of nibrin in response to radiation exposure Divergent hTAFII31-binding motifs hidden in activation domains Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response Regulation and localization of the Bloom syndrome protein in response to DNA damage Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks Cloning and characterization of a p53-related protein kinase expressed in interleukin-2-activated cytotoxic T-cells, epithelial tumor cell lines, and the testes SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint ARF-dependent regulation of ATM and p53 associated KZNF (Apak) protein activity in response to oncogenic stress USP10 regulates p53 localization and stability by deubiquitinating p53 Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress The stress kinase MRK contributes to regulation of DNA damage checkpoints through a p38gamma-independent pathway ATM-dependent phosphorylation of ATF2 is required for the DNA damage response p53 target gene AEN is a nuclear exonuclease required for p53-dependent apoptosis Induction of SOX4 by DNA damage is critical for p53 stabilization and function Targeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53 A role for DEAD box 1 at DNA double-strand breaks DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints Ku86 autoantigen related protein-1 transcription initiates from a CpG island and is induced by p53 through a nearby p53 response element UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization Autophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival.COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1 Regulation of p53 function and stability by phosphorylation Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53 Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage Multiple roles of ATM in monitoring and maintaining DNA integrity Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

P2860

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P2860

Enhanced phosphorylation of p53 by ATM in response to DNA damage

http://www.wikidata.org/entity/Q28609838

description

1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Science

@fr

artículu científicu espublizáu en 1998

@ast

im September 1998 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1998/09/11)

@sk

vědecký článek publikovaný v roce 1998

@cs

wetenschappelijk artikel (gepubliceerd op 1998/09/11)

@nl

наукова стаття, опублікована у вересні 1998

@uk

name

Enhanced phosphorylation of p53 by ATM in response to DNA damage

@ast

Enhanced phosphorylation of p53 by ATM in response to DNA damage

@en

Enhanced phosphorylation of p53 by ATM in response to DNA damage

@nl

type

label

Enhanced phosphorylation of p53 by ATM in response to DNA damage

@ast

Enhanced phosphorylation of p53 by ATM in response to DNA damage

@en

Enhanced phosphorylation of p53 by ATM in response to DNA damage

@nl

prefLabel

Enhanced phosphorylation of p53 by ATM in response to DNA damage

@ast

Enhanced phosphorylation of p53 by ATM in response to DNA damage

@en

Enhanced phosphorylation of p53 by ATM in response to DNA damage

@nl

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SCIENCE.281.5383.1674

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

@en

P2093

C. Prives

http://www.w3.org/2001/XMLSchema#string

C. W. Anderson

http://www.w3.org/2001/XMLSchema#string

L. Chessa

http://www.w3.org/2001/XMLSchema#string

L. Moyal

http://www.w3.org/2001/XMLSchema#string

N. I. Smorodinsky

http://www.w3.org/2001/XMLSchema#string

S. Banin

http://www.w3.org/2001/XMLSchema#string

S. Shieh

http://www.w3.org/2001/XMLSchema#string

Y. Reiss

http://www.w3.org/2001/XMLSchema#string

Y. Shiloh

http://www.w3.org/2001/XMLSchema#string

Y. Taya

http://www.w3.org/2001/XMLSchema#string

P304

1674–1677

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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904050

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10.1126/SCIENCE.281.5383.1674

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5383

http://www.w3.org/2001/XMLSchema#string

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281

http://www.w3.org/2001/XMLSchema#string

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1998-09-11T00:00:00Z

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13551324

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9733514

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phosphorylation