CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures.
about
MicroRNAs in the pathophysiology and treatment of status epilepticusDual and Opposing Roles of MicroRNA-124 in Epilepsy Are Mediated through Inflammatory and NRSF-Dependent Gene Networks.Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death.RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis.Complex network-driven view of genomic mechanisms underlying Parkinson's disease: analyses in dorsal motor vagal nucleus, locus coeruleus, and substantia nigraIschemia/reperfusion-induced CHOP expression promotes apoptosis and impairs renal function recovery: the role of acidosis and GPR4Hypothermic Preconditioning of Human Cortical Neurons Requires Proteostatic PrimingIdentification of microRNAs with Dysregulated Expression in Status Epilepticus Induced EpileptogenesisThe induction of thioredoxin-1 by epinephrine withdraws stress via interaction with β-arrestin-1.microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus.Contribution of apoptosis-associated signaling pathways to epileptogenesis: lessons from Bcl-2 family knockouts.Spatiotemporal progression of ubiquitin-proteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury.Potent Anti-seizure Effects of Locked Nucleic Acid Antagomirs Targeting miR-134 in Multiple Mouse and Rat Models of Epilepsy.Cadmium and cellular signaling cascades: interactions between cell death and survival pathways.microRNA and Epilepsy.Activation of SK2 channels preserves ER Ca²⁺ homeostasis and protects against ER stress-induced cell death.De-repression of myelin-regulating gene expression after status epilepticus in mice lacking the C/EBP homologous protein CHOPChopping Out CHOP Chops the Fate of Neurons.Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in miceIncreased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079.Antagomirs targeting microRNA-134 increase hippocampal pyramidal neuron spine volume in vivo and protect against pilocarpine-induced status epilepticus.Protective neuronal induction of ATF5 in endoplasmic reticulum stress induced by status epilepticus.Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug-refractory epilepsy.Overexpression of 14-3-3ζ Increases Brain Levels of C/EBP Homologous Protein CHOP.Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy.Targeting of microRNA-199a-5p protects against pilocarpine-induced status epilepticus and seizure damage via SIRT1-p53 cascade.The intracellular domain of L1CAM binds to casein kinase 2α and is neuroprotective via inhibition of the tumor suppressors PTEN and p53.Role of endoplasmic reticulum stress via the PERK signaling pathway in brain injury from status epilepticus.Complex spectrum of phenobarbital effects in a mouse model of neonatal hypoxia-induced seizuresBi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus
P2860
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P2860
CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures.
description
2013 nî lūn-bûn
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2013年の論文
@ja
2013年学术文章
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2013年学术文章
@zh
2013年学术文章
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2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
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2013年學術文章
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2013年學術文章
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name
CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures.
@en
CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures.
@nl
type
label
CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures.
@en
CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures.
@nl
prefLabel
CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures.
@en
CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures.
@nl
P2093
P50
P356
P1433
P1476
CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures.
@en
P2093
Alba Jimenez-Pacheco
Amaya Sanz-Rodgriguez
Caoimhin G Concannon
Catherine Moran
Donncha F O'Brien
Emilie Petit
Eva M Jimenez-Mateos
Guillaume Mesuret
Jochen H M Prehn
Michael A Farrell
P304
P356
10.1093/BRAIN/AWS337
P407
P577
2013-01-29T00:00:00Z