Efficacy of preerythrocytic and blood-stage malaria vaccines can be assessed in small sporozoite challenge trials in human volunteers.
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Profiling the host response to malaria vaccination and malaria challengePlasmodium vivax Controlled Human Malaria Infection - Progress and ProspectsSporozoite immunization of human volunteers under mefloquine prophylaxis is safe, immunogenic and protective: a double-blind randomized controlled clinical trialMeasurement of parasitological data by quantitative real-time PCR from controlled human malaria infection trials at the Walter Reed Army Institute of Research.Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites.Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injectionIncreased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studiesImpact of malaria preexposure on antiparasite cellular and humoral immune responses after controlled human malaria infection.Lessons learnt from the first controlled human malaria infection study conducted in Nairobi, KenyaControlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity ratesThe Power of Malaria Vaccine Trials Using Controlled Human Malaria Infection.NF135.C10: a new Plasmodium falciparum clone for controlled human malaria infections.Safety, Immunogenicity, and Protective Efficacy of Intradermal Immunization with Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites in Volunteers Under Chloroquine Prophylaxis: A Randomized Controlled Trial.Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity.Comparison of modeling methods to determine liver-to-blood inocula and parasite multiplication rates during controlled human malaria infectionChanges in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection.Challenges of assessing the clinical efficacy of asexual blood-stage Plasmodium falciparum malaria vaccinesAddressing the bottleneck at clinical testing of candidate malaria vaccines.Infectivity of Plasmodium falciparum sporozoites determines emerging parasitemia in infected volunteers.Malaria sporozoite challenge model comes of age.Vaccines to Accelerate Malaria Elimination and Eventual Eradication.A framework for Controlled Human Infection Model (CHIM) studies in Malawi: Report of a Wellcome Trust workshop on CHIM in Low Income Countries held in Blantyre, Malawi.Taking a bite out of malaria: controlled human malaria infection by needle and syringeWhole blood transcriptome changes following controlled human malaria infection in malaria pre-exposed volunteers correlate with parasite prepatent period.Plasmodium 18S rRNA of intravenously administered sporozoites does not persist in peripheral blood
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P2860
Efficacy of preerythrocytic and blood-stage malaria vaccines can be assessed in small sporozoite challenge trials in human volunteers.
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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name
Efficacy of preerythrocytic an ...... ge trials in human volunteers.
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Efficacy of preerythrocytic an ...... ge trials in human volunteers.
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type
label
Efficacy of preerythrocytic an ...... ge trials in human volunteers.
@en
Efficacy of preerythrocytic an ...... ge trials in human volunteers.
@nl
prefLabel
Efficacy of preerythrocytic an ...... ge trials in human volunteers.
@en
Efficacy of preerythrocytic an ...... ge trials in human volunteers.
@nl
P2093
P356
P1476
Efficacy of preerythrocytic an ...... ge trials in human volunteers.
@en
P2093
An-Emmie Nieman
Cornelus C Hermsen
Meta Roestenberg
Sake J de Vlas
P304
P356
10.1093/INFDIS/JIS355
P407
P577
2012-05-21T00:00:00Z