Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology.
about
Novel therapeutics for Alzheimer's disease: an updateIdentification of a regulatory loop for the synthesis of neurosteroids: a steroidogenic acute regulatory protein-dependent mechanism involving hypothalamic-pituitary-gonadal axis receptorsThe endocrine dyscrasia that accompanies menopause and andropause induces aberrant cell cycle signaling that triggers re-entry of post-mitotic neurons into the cell cycle, neurodysfunction, neurodegeneration and cognitive diseaseLuteinizing hormone receptor mediates neuronal pregnenolone production via up-regulation of steroidogenic acute regulatory protein expressionDown-regulation of serum gonadotropins is as effective as estrogen replacement at improving menopause-associated cognitive deficits.Gonadotropin-releasing hormone receptor system: modulatory role in aging and neurodegeneration.Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition.Preliminary Hormonal Correlations in Female Patients as a Function of Somatic and Neurological Symptom Clusters: An Exploratory Development of a Multi-Hormonal Map for Bio-Identical Replacement Therapy (MHRT).Oxidative stress, testosterone, and cognition among Caucasian and Mexican-American men with and without Alzheimer's diseaseKnowledge-based compact disease models identify new molecular players contributing to early-stage Alzheimer's disease.Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer diseaseFrontiers in Alzheimer's disease therapeutics.Investigational drugs for the treatment of AD: what can we learn from negative trials?Advances in endocrinology of aging research, 2005-2006Dysregulation of the hypothalamic-pituitary-gonadal axis with menopause and andropause promotes neurodegenerative senescence.The contribution of luteinizing hormone to Alzheimer disease pathogenesisHuman chorionic gonadotropin (a luteinizing hormone homologue) decreases spatial memory and increases brain amyloid-beta levels in female rats.The effects of testosterone on cognition in elderly men: a review.Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice.Extrapituitary production of anterior pituitary hormones: an overview.Road to Alzheimer's disease: the pathomechanism underlying.Knowledge-Based Compact Disease Models: A Rapid Path from High-Throughput Data to Understanding Causative Mechanisms for a Complex Disease.The endocrine-brain-aging triad where many paths meet: female reproductive hormone changes at midlife and their influence on circuits important for learning and memory.Progress in the development of new drugs in Alzheimer's disease.Expression of Luteinizing Hormone (LH) Subunit Genes in Mouse TestisReciprocal induction between α-synuclein and β-amyloid in adult rat neurons.Direct exposure of guinea pig CNS to human luteinizing hormone increases cerebrospinal fluid and cerebral beta amyloid levels.Associations between gonadotropins, testosterone and β amyloid in men at risk of Alzheimer's disease.Involvement of Luteinizing Hormone in Alzheimer Disease Development in Elderly Women.Nonestrogen-based hormonal therapies for Alzheimer’s disease
P2860
Q24620383-9E7283A4-7C3A-48CC-99E5-1B83C2E56236Q24645044-796A9CB6-E715-4AE5-92E3-AB84D92F2665Q26799258-D2628202-5B5B-456F-B854-031F7FF6A2A6Q28568570-6407B4CF-6AD0-4B27-854E-6C2A31CF8F99Q33915170-9BE82DBD-A606-4F88-8DAE-857B7C39424DQ34258591-330E67B9-23BE-4057-A3BC-E57C26C0706DQ34297011-0A0DB722-82C3-4572-88D1-9B1C95A37D37Q34307863-0F573C5A-A034-4565-97F8-9CE78BD845F6Q34449460-22A82D52-81AB-4A9D-BD4B-000EB52E285EQ35033039-5F90DDE8-CA74-4938-BA67-620F9192474AQ35070362-B0362AEB-CB41-433B-A346-455A475BF2B5Q35086876-18A51A18-8304-4BB5-9780-A44F6D85AA6DQ35579234-B35EDCC3-86D9-4D0A-B90B-9892D8EF9A53Q35649220-71C8AD6D-1E2D-487D-BF4B-DA93E10C12C3Q36063538-D8191D0D-10B0-487D-BFDA-DA74CE0A7E20Q36203397-FEA899A1-4A53-4786-A7D3-4BF3788FA24CQ37036997-8D0E19AC-AE5D-4372-817E-56F099D98EF3Q37310152-B3A8114D-B4DF-4195-91C9-BA4AC962B03FQ37372709-6A98C5FF-869A-4534-AC5F-E6C05EE44250Q37968477-DE3D793E-E565-482A-A184-484782A3A1EAQ37972068-54620960-931E-447E-969B-FA388CD3B654Q38371546-6E564FC8-797E-4875-9187-E615C113250FQ39039985-D645A591-63FF-436D-AA76-E1BB832D975BQ39789745-6FCB0E73-8765-499E-B1BC-F2EAA7E57340Q42653934-B60F9959-AEE3-44C4-889F-A3320B455927Q43721592-ACC091E3-59DC-480E-97F5-75DD94D57D40Q43893803-D501FF34-FA4C-4D55-98AB-A88F7203DA8BQ48325860-164B49FD-B087-41FD-B884-4157129A2872Q48614782-924E5523-7528-4B1C-AA8E-827900405CC6Q57341506-3058B80F-36AB-466C-B6BE-8C353F7D4185
P2860
Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Elevated luteinizing hormone e ...... Alzheimer's disease pathology.
@en
Elevated luteinizing hormone e ...... Alzheimer's disease pathology.
@nl
type
label
Elevated luteinizing hormone e ...... Alzheimer's disease pathology.
@en
Elevated luteinizing hormone e ...... Alzheimer's disease pathology.
@nl
prefLabel
Elevated luteinizing hormone e ...... Alzheimer's disease pathology.
@en
Elevated luteinizing hormone e ...... Alzheimer's disease pathology.
@nl
P2093
P2860
P356
P1476
Elevated luteinizing hormone e ...... Alzheimer's disease pathology.
@en
P2093
Craig S Atwood
Peggy L R Harris
Ralph N Martins
Richard L Bowen
Rudolph J Castellani
Zvezdana Kubat
P2860
P304
P356
10.1002/JNR.10452
P577
2002-11-01T00:00:00Z