Src activation regulates anoikis in human colon tumor cell lines.
about
Involvement of Src tyrosine kinase in Escherichia coli invasion of human brain microvascular endothelial cellsA novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathwaysDok-R mediates attenuation of epidermal growth factor-dependent mitogen-activated protein kinase and Akt activation through processive recruitment of c-Src and Csk.Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitorsCUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinomaThe molecular rationale of Src inhibition in colorectal carcinomasComputational models reveal a passive mechanism for cell migration in the cryptA two-dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheathDomain-specific function of ShcC docking protein in neuroblastoma cellsCombined Inhibition of IGF-1R/IR and Src family kinases enhances antitumor effects in prostate cancer by decreasing activated survival pathwaysData-Driven Discovery of Extravasation Pathway in Circulating Tumor Cells.A phase II trial of the Src-kinase inhibitor saracatinib after four cycles of chemotherapy for patients with extensive stage small cell lung cancer: NCCTG trial N-0621.Migfilin interacts with Src and contributes to cell-matrix adhesion-mediated survival signaling.Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.Understanding molecular mechanisms in peritoneal dissemination of colorectal cancer : future possibilities for personalised treatment by use of biomarkers.Apoptosis-associated tyrosine kinase 1 inhibits growth and migration and promotes apoptosis in melanoma.ERK-regulated αB-crystallin induction by matrix detachment inhibits anoikis and promotes lung metastasis in vivo.CD99 acts as an oncosuppressor in osteosarcomaPhosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers.CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.Homeostatic properties of Lactobacillus jensenii engineered as a live vaginal anti-HIV microbicideDasatinib in previously treated metastatic colorectal cancer: a phase II trial of the University of Chicago Phase II Consortium.Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells.Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model.Understanding micrometastatic disease and Anoikis resistance in ewing family of tumors and osteosarcoma.Tumor-Associated Endothelial Cells Promote Tumor Metastasis by Chaperoning Circulating Tumor Cells and Protecting Them from AnoikisYes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells.Novel Bioluminescent Activatable Reporter for Src Tyrosine Kinase Activity in Living Mice.Protein Kinase A Activation Promotes Cancer Cell Resistance to Glucose Starvation and AnoikisActive participation of endothelial cells in inflammation.Inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation on tumor-associated endothelial cells leads to treatment of orthotopic human colon cancer in nude miceA plant alkaloid, veratridine, potentiates cancer chemosensitivity by UBXN2A-dependent inhibition of an oncoprotein, mortalin-2.Claudin-1 expression confers resistance to anoikis in colon cancer cells in a Src-dependent mannerAnoikis, initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesisDownstream intracellular effectors of epidermal growth factor receptor as targets for anticancer therapy.Apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by PTP alpha and src RNAi.Is there a genetic signature for liver metastasis in colorectal cancer?Ligand-independent activation of MET through IGF-1/IGF-1R signaling.The transmembrane src substrate Trask is an epithelial protein that signals during anchorage deprivation.Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress
P2860
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P2860
Src activation regulates anoikis in human colon tumor cell lines.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Src activation regulates anoikis in human colon tumor cell lines.
@en
Src activation regulates anoikis in human colon tumor cell lines.
@nl
type
label
Src activation regulates anoikis in human colon tumor cell lines.
@en
Src activation regulates anoikis in human colon tumor cell lines.
@nl
prefLabel
Src activation regulates anoikis in human colon tumor cell lines.
@en
Src activation regulates anoikis in human colon tumor cell lines.
@nl
P2093
P2860
P356
P1433
P1476
Src activation regulates anoikis in human colon tumor cell lines.
@en
P2093
Alan J Kraker
David J McConkey
Doris R Siwak
Gary E Gallick
Justin M Summy
Nila U Parikh
T Christopher Windham
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205989
P407
P577
2002-11-01T00:00:00Z