Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer. - Wikidata - awgldk - TriplyDB

Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.

Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.

http://www.wikidata.org/entity/Q34109397

about

The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: new therapeutic targets Regulation of SRC family kinases in human cancers A network-based biomarker approach for molecular investigation and diagnosis of lung cancer.Novel dual Src/Abl inhibitors for hematologic and solid malignancies.Jak/STAT pathways in cytokine signaling and myeloproliferative disorders: approaches for targeted therapies.Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells Combined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growth MiR-130b is a prognostic marker and inhibits cell proliferation and invasion in pancreatic cancer through targeting STAT3 Identification and characterization of a suite of tumor targeting peptides for non-small cell lung cancer.Response to combined molecular targeting: defining the role of P-STAT3.Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy Src inhibitors in suppression of papillary thyroid carcinoma growth.Digoxin Suppresses Tumor Malignancy through Inhibiting Multiple Src-Related Signaling Pathways in Non-Small Cell Lung Cancer STAT5A-mediated SOCS2 expression regulates Jak2 and STAT3 activity following c-Src inhibition in head and neck squamous carcinoma Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy.Proteomic profiling identifies pathways dysregulated in non-small cell lung cancer and an inverse association of AMPK and adhesion pathways with recurrence.Targeted inhibition of SRC kinase signaling attenuates pancreatic tumorigenesis.An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance.Epithelial-Mesenchymal Transition Predicts Polo-Like Kinase 1 Inhibitor-Mediated Apoptosis in Non-Small Cell Lung Cancer.KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib.c-Src/Cav1-dependent activation of the EGFR by Dsg2 GRIM-19 mutations fail to inhibit v-Src-induced oncogenesis.MLS-2384, a new 6-bromoindirubin derivative with dual JAK/Src kinase inhibitory activity, suppresses growth of diverse cancer cells Targeted inhibition of Src kinase with dasatinib blocks thyroid cancer growth and metastasis.STAT3 signaling in pulmonary arterial hypertension.Genetic Interactions of STAT3 and Anticancer Drug Development.The Role of STAT3 in Non-Small Cell Lung Cancer.15α-methoxypuupehenol Induces Antitumor Effects In Vitro and In Vivo against Human Glioblastoma and Breast Cancer Models.IFNs-signaling effects on lung cancer: an up-to-date pathways-specific review.The role of JAK/STAT3 signaling pathway on apoptosis of lung adenocarcinoma cell line PC-9 induced by icotinib.Src and STAT3 inhibitors synergize to promote tumor inhibition in renal cell carcinoma.A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells.Inhibition of related JAK/STAT pathways with molecular targeted drugs shows strong synergy with ruxolitinib in chronic myeloproliferative neoplasm.Resistance of Cancer Cells to Targeted Therapies Through the Activation of Compensating Signaling Loops.Protective effects of ADAM8 against cisplatin-mediated apoptosis in non-small-cell lung cancer.Stat3 is a positive regulator of gap junctional intercellular communication in cultured, human lung carcinoma cells.Down-regulation of STAT3 expression by vector-based small interfering RNA inhibits pancreatic cancer growth Stat3 and gap junctions in normal and lung cancer cells.Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers.Src Promotes Metastasis of Human Non-Small Cell Lung Cancer Cells through Fn14-Mediated NF-κB Signaling.

P2860

Q26782593-8375216F-A18A-40DB-A98D-3667A5CFF32F Q28243770-6DA4E82B-59E7-4CD8-829C-267B7815FD67 Q33787452-88ACAC51-E458-45D5-A7A5-19F7D60D5ECA Q34121339-F59BA40F-6B45-46FF-898A-1B07E8466503 Q34718163-2FC6E6E3-B2E6-4AF5-81A8-242E07716EE9 Q34795689-E92E58B4-0D64-4FA1-BA89-46FE3B3DABDF Q34812100-5656E198-C052-489E-BF7A-469904273DF2 Q34989346-BDE88F75-5816-42F8-9C1A-9CCB57B2D456 Q35131992-2EE75E3C-4F3E-410C-A6BA-C997DF98D9F7 Q35146581-86598ED2-2CB4-4A22-ADC2-AAC922790B90 Q35174944-1822C3E2-0372-4D58-9251-02CA3FFAC39D Q35457965-006C892C-6132-4C29-8E9B-D436E38BAD56 Q35587056-5FD868DA-01C5-4459-94B8-713CA0924731 Q35653082-9B15CE1A-0A78-4E4E-9016-1B2EED885AA1 Q35882137-FDA35B8E-A858-4778-A5F5-7F0AB7957F70 Q36030339-1469A673-DFF0-4A67-B169-978B60EE665A Q36253834-E1114DFF-6E56-43F9-9A77-67B727B7D234 Q36597042-192DBA1D-DDB6-49FE-BFBF-A1345FD46486 Q36759439-AB0EF281-BCA7-429A-B03A-C5B5E85B7DDD Q36805595-120CA7E1-71F1-4DD8-AD8B-3A56A36BB192 Q37437211-33C62186-6914-4204-A3C1-174FFA26DCAF Q37565038-69EB7B10-EB8B-4323-900F-A6DD953844E8 Q37591464-633FA789-6EEB-4364-AA61-4A2518E4AA3E Q37597360-EB398EF2-E388-43D0-9AC5-A5AE40D1C3E4 Q38140894-0FC2FE03-29BD-44B9-82B1-F7005DD17FBA Q38198930-A3E97433-4883-4962-BECD-904204D786BC Q38199934-C9A70C90-9EC1-4466-8A1C-B6891BD1104D Q38722193-F751EEC0-E7A6-4CF0-A721-B4B87A2FA34B Q38758152-FF6EC5ED-D218-41FC-82B6-26788CB00D9A Q38770483-625A132B-FAAA-4035-82FE-1CCEB8A0B7BA Q38815335-72747EE7-7160-46C8-BC8C-B9EC85FBB5A6 Q39121242-843F05AA-4FF0-43B5-8F42-401350DCFA19 Q39170744-2FF25528-45B7-4408-82DE-9767D00E95D2 Q39203633-DD38F7B4-7B92-4401-8EB4-6B3D52F42E3C Q39210507-3C87FBBE-82EF-4D6B-BC93-6AD97EF13C71 Q39225410-996ADE34-768A-4887-A9ED-7ABB9F6DE5E3 Q39498818-69F584D4-4681-4EBA-A415-9339AF113A5A Q41457047-BEB7DD6A-32DD-433D-B40A-4BBEFE970D22 Q47423597-FCF7960B-0EC0-44BF-82A8-8232EC6D628D Q54983459-2DA177BA-8FCE-4A94-88D0-A28C17C8902A

P2860

Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.

http://www.wikidata.org/entity/Q34109397

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.

@ast

Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.

@en

Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.

@nl

type

label

Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.

@ast

Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.

@en

Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.

@nl

prefLabel

Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.

@ast

Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.

@en

Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.

@nl

P1433

Q34109397-D82BDD56-852A-4816-903D-AF9F859B97AB

P1476

Q34109397-4842D3E2-F46A-4986-AFB3-A3BE40B0F4B4

P2093

Q34109397-176258A0-265C-47A5-8EDB-FE27D305CD94

Q34109397-1CE0CDD9-F42D-4B33-8446-6849367DC02A

Q34109397-1EC64E55-A165-4143-BE22-FF7D198A5035

Q34109397-4FE2DF41-23CB-48BF-BB75-BF4D9A03664A

Q34109397-8692DE53-9703-468F-9BC4-F991DAE1FD60

Q34109397-89BB5E92-F2C8-45CC-BDA3-3EFAF198C324

Q34109397-926501DE-90A9-4169-A4B3-2E03C20D16AB

Q34109397-AB4DE79F-085A-4A7A-800C-80838C83307F

Q34109397-B57DBF8E-84F7-44E7-A878-098A9180C0FC

P2860

Q34109397-07E2E6E7-D647-44C5-AB0C-1280EED7885D

Q34109397-0874058A-556B-4C9C-A2E0-021595F326CE

Q34109397-0A30C510-9164-4191-84B4-AFF312B47F00

Q34109397-0A53EC0E-4B84-4261-B359-555ACEDA3376

Q34109397-0A697436-EFD5-48ED-9E02-1A85FAA45D95

Q34109397-0E1F7E76-B6CE-4351-B06C-DFE8A43D5B2B

Q34109397-0FE4FE06-7F9C-4F71-8638-3C157D1FAD32

Q34109397-243B96F0-ABE3-406A-A844-7123A76C3D8B

Q34109397-2556AA45-88F9-4C6D-AD50-00567802ACDD

Q34109397-2CB749D4-C3F3-4C44-BA2A-CEE96A31626C

P304

Q34109397-36C98042-9918-43D3-9A09-9A70516618DB

P31

Q34109397-84D67A2E-1BB7-4D43-AF6B-35416DC5FE78

P356

Q34109397-5BA3109C-C14A-4F75-AA31-6F0D29EDDCF5

P407

Q34109397-C60B3D43-74E4-4127-B772-932EAEE356C2

P433

Q34109397-3707F7E0-F06F-449B-AB13-4C197CD0C74B

P478

Q34109397-84A34583-1B5F-40C5-8861-FB7491F6F6B1

P50

Q34109397-E662BB05-188D-4BEF-B9CE-C9B18E120180

P577

Q34109397-F1364C93-A1E0-4BBE-9A95-B303939DDD15

P698

Q34109397-207E573A-F59F-4935-BB73-01D4500F43DC

P932

Q34109397-978D22DE-C894-40AC-A715-9646DD07644F

P356

1078-0432.CCR-09-0767

P1433

Clinical Cancer Research

P1476

Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.

@en

P2093

Babita Saigal

http://www.w3.org/2001/XMLSchema#string

Banibrata Sen

http://www.w3.org/2001/XMLSchema#string

Faye M Johnson

http://www.w3.org/2001/XMLSchema#string

Gordon B Mills

http://www.w3.org/2001/XMLSchema#string

Jing Wang

http://www.w3.org/2001/XMLSchema#string

Lauren Averett Byers

http://www.w3.org/2001/XMLSchema#string

Lixia Diao

http://www.w3.org/2001/XMLSchema#string

Meera Nanjundan

http://www.w3.org/2001/XMLSchema#string

Tina Cascone

http://www.w3.org/2001/XMLSchema#string

P2860

KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib

Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling.

Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia vera.

TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src

The STATs of cancer--new molecular targets come of age

Cellular functions regulated by Src family kinases

A renaissance for SRC

Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells.

STAT signaling in head and neck cancer.

P304

6852-6861

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1158/1078-0432.CCR-09-0767

http://www.w3.org/2001/XMLSchema#string

P407

P433

22

http://www.w3.org/2001/XMLSchema#string

P478

15

http://www.w3.org/2001/XMLSchema#string

P50

P577

2009-10-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

19861436

http://www.w3.org/2001/XMLSchema#string

P932

2935176

http://www.w3.org/2001/XMLSchema#string