Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine.
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Neuralized1 causes apoptosis and downregulates Notch target genes in medulloblastomaFootprinting of mammalian promoters: use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule levelEvidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell linesDNA methylation and histone H3-K9 modifications contribute to MUC17 expressionEpigenetic alterations in agingSALL3 interacts with DNMT3A and shows the ability to inhibit CpG island methylation in hepatocellular carcinomaCharacteristic promoter hypermethylation signatures in male germ cell tumorsGlobal histone post-translational modifications and cancer: Biomarkers for diagnosis, prognosis and treatment?Next-Generation Sequencing Approaches in Cancer: Where Have They Brought Us and Where Will They Take Us?Epigenetic Therapy for Solid Tumors: Highlighting the Impact of Tumor HypoxiaDNA methylation pathways and their crosstalk with histone methylationStructural and functional coordination of DNA and histone methylationHistone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and preventionEpigenetics meets radiation biology as a new approach in cancer treatmentMPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9aAdvancements in the delivery of epigenetic drugsEffect of phenylhexyl isothiocyanate on aberrant histone H3 methylation in primary human acute leukemiaAn unmethylated 3' promoter-proximal region is required for efficient transcription initiationGene reactivation by 5-aza-2'-deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regionsAssociation of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatinEpigenetics in cancerDemethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists.A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencingDiverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing.CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cellsIntroduction--Epiphanies in epigenetics.Modulation of microRNA expression in human lung cancer cells by the G9a histone methyltransferase inhibitor BIX01294.Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promotersEpigenetic changes in the myelodysplastic syndrome.Epigenetic Targeting of Transforming Growth Factor β Receptor II and Implications for Cancer TherapyCoordinated chromatin control: structural and functional linkage of DNA and histone methylation.Hypoxia-induced down-regulation of neprilysin by histone modification in mouse primary cortical and hippocampal neurons.Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome.Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylationCoordinated changes in DNA methylation and histone modifications regulate silencing/derepression of luteinizing hormone receptor gene transcriptionMethyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer.Chronic prenatal hypoxia induces epigenetic programming of PKC{epsilon} gene repression in rat hearts.Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9.Constant p53 pathway inactivation in a large series of soft tissue sarcomas with complex genetics.Re-expression of methylation-induced tumor suppressor gene silencing is associated with the state of histone modification in gastric cancer cell lines.
P2860
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P2860
Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
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2002年學術文章
@yue
2002年學術文章
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name
Histone H3-lysine 9 methylatio ...... sed by 5-aza-2'-deoxycytidine.
@en
Histone H3-lysine 9 methylatio ...... sed by 5-aza-2'-deoxycytidine.
@nl
type
label
Histone H3-lysine 9 methylatio ...... sed by 5-aza-2'-deoxycytidine.
@en
Histone H3-lysine 9 methylatio ...... sed by 5-aza-2'-deoxycytidine.
@nl
prefLabel
Histone H3-lysine 9 methylatio ...... sed by 5-aza-2'-deoxycytidine.
@en
Histone H3-lysine 9 methylatio ...... sed by 5-aza-2'-deoxycytidine.
@nl
P2093
P1433
P1476
Histone H3-lysine 9 methylatio ...... sed by 5-aza-2'-deoxycytidine.
@en
P2093
Carvell T Nguyen
Daniel J Weisenberger
Felicidad A Gonzales
Gangning Liang
Joy C Y Lin
Mihaela Velicescu
Peter A Jones
P304
P407
P577
2002-11-01T00:00:00Z