Assignment of molecular properties of a superactive coagulation factor VIIa variant to individual amino acid changes.
about
Mechanism of the Ca2+-induced Enhancement of the Intrinsic Factor VIIa ActivityDisulfide locked variants of factor VIIa with a restricted beta-strand conformation have enhanced enzymatic activityRecent estimates of the structure of the factor VIIa (FVIIa)/tissue factor (TF) and factor Xa (FXa) ternary complex.Catalytic domain modification and viral gene delivery of activated factor VII confers hemostasis at reduced expression levels and vector doses in vivo.Augmented intrinsic activity of Factor VIIa by replacement of residues 305, 314, 337 and 374: evidence of two unique mutational mechanisms of activity enhancement.Factor VIIa analogue (V158D/E296V/M298Q-FVIIa) normalises clot formation in whole blood from patients with severe haemophilia A.An all-atom solution-equilibrated model for human extrinsic blood coagulation complex (sTF-VIIa-Xa): a protein-protein docking and molecular dynamics refinement study.A loop of coagulation factor VIIa influencing macromolecular substrate specificity
P2860
Q27651260-97938F19-16DB-4CAA-BE43-7F01038A9DF0Q33214236-1AD0CE7E-68EC-451B-804D-469D5CEC187EQ37692638-58B015EE-42A5-4E60-B94A-E4CC5899F7ABQ39591239-51B4EC91-D0BC-4F48-BD4E-81C606800E95Q41876554-51EEE0D6-08AC-4172-BD4A-7CE24C81F530Q45866930-22E7D845-B7EB-483E-956B-92B50FD56674Q47233926-E31DEAA5-B2A2-49CF-9404-C8A1ADE3AD3CQ58211010-2A926DB2-7FEB-469B-B763-B90EDADD05F1
P2860
Assignment of molecular properties of a superactive coagulation factor VIIa variant to individual amino acid changes.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Assignment of molecular proper ...... individual amino acid changes.
@en
Assignment of molecular proper ...... individual amino acid changes.
@nl
type
label
Assignment of molecular proper ...... individual amino acid changes.
@en
Assignment of molecular proper ...... individual amino acid changes.
@nl
prefLabel
Assignment of molecular proper ...... individual amino acid changes.
@en
Assignment of molecular proper ...... individual amino acid changes.
@nl
P2860
P1433
P1476
Assignment of molecular proper ...... individual amino acid changes
@en
P2093
Ole H Olsen
P2860
P304
P356
10.1046/J.1432-1033.2002.03323.X
P407
P50
P577
2002-12-01T00:00:00Z