Genotoxicity, toxicity, and carcinogenicity of the antihistamine methapyrilene.
about
Overview of an interlaboratory collaboration on evaluating the effects of model hepatotoxicants on hepatic gene expression.Gene expression analysis of the hepatotoxicant methapyrilene in primary rat hepatocytes: an interlaboratory study.Quinoline: unscheduled DNA synthesis and mitogenesis data from the rat liver in vivo.Toxicogenomics in drug discovery and drug development: potential applications and future challenges.Genotoxicity and carcinogenicity studies of antihistamines.Literature-based compound profiling: application to toxicogenomics.Perspective on the usefulness of the mouse lymphoma assay as an indicator of a genotoxic carcinogen: ten compounds which are positive in the mouse lymphoma assay but are not genotoxic carcinogens.An evaluation of the CHO/HGPRT mutation assay involving suspension cultures and soft agar cloning: results for 33 chemicals.Methapyrilene toxicity: anchorage of pathologic observations to gene expression alterations.In vitro to in vivo extrapolation and species response comparisons for drug-induced liver injury (DILI) using DILIsym™: a mechanistic, mathematical model of DILI.Assay-specific genotoxicity of N-nitrosodibenzylamine to the rat liver in vivo.Comparisons of protein changes in human and rodent hepatocytes induced by the rat-specific carcinogen, methapyrilene.DNA methylation and oncogene expression in methapyrilene-induced rat liver tumors and in treated hepatocytes in culture.Mitogenic activity of quinoline to the rat, mouse, and guinea pig liver: empirical correlations with hepatic carcinogenicity.
P2860
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P2860
Genotoxicity, toxicity, and carcinogenicity of the antihistamine methapyrilene.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh
1987年學術文章
@zh-hant
name
Genotoxicity, toxicity, and carcinogenicity of the antihistamine methapyrilene.
@en
Genotoxicity, toxicity, and carcinogenicity of the antihistamine methapyrilene.
@nl
type
label
Genotoxicity, toxicity, and carcinogenicity of the antihistamine methapyrilene.
@en
Genotoxicity, toxicity, and carcinogenicity of the antihistamine methapyrilene.
@nl
prefLabel
Genotoxicity, toxicity, and carcinogenicity of the antihistamine methapyrilene.
@en
Genotoxicity, toxicity, and carcinogenicity of the antihistamine methapyrilene.
@nl
P1433
P1476
Genotoxicity, toxicity, and carcinogenicity of the antihistamine methapyrilene.
@en
P304
P356
10.1016/0165-1110(87)90022-4
P407
P577
1987-05-01T00:00:00Z